Fig. 2
From: Deficiency of innate-like T lymphocytes in chronic obstructive pulmonary disease
Peripheral blood MAIT cells of healthy controls (HC), stable COPD and AECOPD patients. a Representative flow cytometry dot-plots of MAIT cells stained with Vα7.2 and CD161 specific antibodies after gating on CD3+ cells. b Significantly decreased MAIT cells were detected in stable COPD and AECOPD patients. c Non-significant increase of DN MAIT subsets was observed in COPD patients compared to the healthy controls. d Significant decrease of CD8+ MAIT subpopulation was enumerated in the peripheral blood of COPD patients. Percentages were calculated after gating on CD3+ T cells. Data present here were derived from seventeen HC, eleven stable COPD and ten AECOPD blood donors. Boxes show interquartile ranges (IQR), whiskers represent lowest and highest values, horizontal lines indicate median, and circles stand for outliers of 1.5 IQR. Asterisks represent significant p (* < 0.05, ** < 0.01, *** < 0.001) values