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Fig. 1 | Respiratory Research

Fig. 1

From: Deficiency of innate-like T lymphocytes in chronic obstructive pulmonary disease

Fig. 1

Peripheral blood iNKT cells of healthy controls (HC), stable COPD and exacerbating COPD (AECOPD) patients. a Representative flow cytometry dot-plots of iNKT cells stained with Vα24-Jα18 and CD3 specific antibodies. b Decreased total iNKT populations were detected in stable COPD and AECOPD patients. c Significantly elevated CD4+ iNKT subpopulation were enumerated in AECOPD patients compared to the controls. d Significantly decreased DN iNKT subsets were observed in AECOPD patients. Percentages were calculated after gating on CD3+ and Vα24-Jα18+ iNKT cells. Data present here were derived from seventeen HC, eleven stable COPD and ten AECOPD blood donors. Boxes show interquartile ranges (IQR), whiskers represent lowest and highest values, horizontal lines indicate median, and circles stand for outliers of 1.5 IQR. Asterisks represent significant p (* < 0.05, ** < 0.01, *** < 0.001) values

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