RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism

Table 5 Genes in dataset #2 part of the three downstream function categories defined by IPA using dataset #1 (Table 2, Figs. 2, 3 and 4)

Downstream function categories (Figs. 2, 3 and 4)	Genes
	Upregulated	Downregulated
Immune response	C3, CH25H, CXCL1, CXCL8, ICAM1, IL6	ERBB3, TLR1
Remodeling	C3, CXCL1, CXCL8, CYP1A1, ICAM1, IL6
Lipid synthesis	C3, CH25H, CXCL1, CXCL8, CYP1A1, IL6, UCN2

ISSN: 1465-993X