Fig. 4

IPA Downstream Analysis as Networks identified functions on lipid metabolism. The association between genes of our dataset #1 (300 genes) and specific functions received an overlap p value and a z-score for prediction of activation or inhibition on the function: “synthesis of lipid”. Nineteen genes from our first dataset either upregulated or downregulated in HLF by the IL3IgG eosinophil conditioned media, are involved in the regulation of this function with a significant z-score toward increased “activation”