Fig. 3

IPA Downstream Analysis as Networks identified functions on tissue remodeling. The association between genes of our dataset #1 (300 genes) and specific functions received an overlap p value and a z-score for prediction of activation or inhibition on the functions: “angiogenesis” and “development of vasculature” and “development of connective tissue cells”. Twenty-nine genes from our first dataset either upregulated or downregulated in HLF by the IL3IgG eosinophil conditioned media, are involved in the regulation of these three functions with a significant z-score toward increased “activation”