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Fig. 2 | Respiratory Research

Fig. 2

From: RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism

Fig. 2

IPA Downstream Analysis as Networks identified functions on the immune response. The association between genes of our dataset #1 (300 genes) and specific downstream functions received an overlap p value and a z-score for prediction of activation or inhibition on the functions: “immune response of cells” and “homing of cells”. Twenty-seven genes from our dataset either upregulated or downregulated in HLF by IL3IgG eosinophil conditioned media, are involved in the regulation of “immune response of cells” and “homing of cells” with a significant z-score toward increased “activation”

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