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Table 2 Semi-quantitative analysis of electron microscopy

From: Ghrelin therapy improves lung and cardiovascular function in experimental emphysema

 

C

ELA

Sal

Ghr

Sal

Ghr

Type 2 epithelial cell damage

0 [0-1]

1 [0-1]

3 [2.5-3.5]*

2 [2-3]

Endothelial cell damage

1 [0-1]

0 [0-0.5]

3 [3-3.5]*

2 [1.5-2.5]#

Collagen fibre

0 [0-0.5]

0 [0-0.5]

3 [2.5-3.5]*

2 [1-2]#

Activated macrophage

0 [0-1]

1 [0-1]

2 [1.5-2]

3 [2.5-3.5]*#

  1. Values are median [interquartile range] of 5 animals per group. C control, ELA elastase-induced emphysema, Sal i.p. injection of saline, Ghr i.p. injection of ghrelin. Pathologic findings were graded on a five-point, semi-quantitative, severity-based scoring system, where 0 = normal lung parenchyma, 1 = changes in 1–25% of examined tissue, 2 = 26–50% of examined tissue, 3 = 51–75% of examined tissue, and 4 = 76–100% of examined tissue. * vs. C-Sal. # vs. ELA-Sal
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Respiratory Research

ISSN: 1465-993X

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