Increased activated regulatory T cells proportion correlate with the severity of idiopathic pulmonary fibrosis

Respiratory Research

Table 1 Demographics of the study participants

	HCs	pSS-IP	IPF	P-value^*
Subjects	n = 23	n = 19	n = 29
Age, years	66.1 ± 8.6	60.6 ± 7.6	65.1 ± 6.2	0.056
Female/male, n	12/11	15/4	1/28	0.000
Smoker/non-smoker, n	10/13	4/15	27/2	0.000
PaO₂, mmHg	94.7 ± 5.9	85.1 ± 16.6	86.6 ± 11.1	0.061
FVC, % predicted	95.2 ± 8.7	71.0 ± 13.1	80.1 ± 18.2	0.000
FEV₁, % predicted	89.3 ± 10.0	70.2 ± 12.5	84.1 ± 18.0	0.000
FEV₁/FVC, %	85.2 ± 3.9	82.4 ± 5.9	81.6 ± 5.8	0.089
TLC, % predicted	88.8 ± 5.0	67.9 ± 11.1	75.6 ± 11.6	0.000
DLCO, % predicted	88.3 ± 4.9	36.9 ± 20.8	43.3 ± 16.5	0.000

Data are presented as the means ± SD or n. ^*: P-value denotes statistical differences among the three groups; DLCO: diffusing capacity of the lung for carbon monoxide; FEV₁: forced expiratory volume in the first second; FVC: forced vital capacity; PaO₂: partial pressure of arterial oxygen; TLC: total lung capacity

ISSN: 1465-993X