TY - JOUR AU - Wong, K. A. AU - Wilson, J. AU - Russo, A. AU - Wang, L. AU - Okur, M. N. AU - Wang, X. AU - Martin, N. P. AU - Scappini, E. AU - Carnegie, G. K. AU - O'Bryan, J. P. PY - 2012 DA - 2012// TI - Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0036023 DO - 10.1371/journal.pone.0036023 ID - Wong2012 ER - TY - JOUR AU - Flynn, D. C. PY - 2001 DA - 2001// TI - Adaptor proteins JO - Oncogene VL - 20 UR - https://doi.org/10.1038/sj.onc.1204769 DO - 10.1038/sj.onc.1204769 ID - Flynn2001 ER - TY - JOUR AU - Yee, D. PY - 2010 DA - 2010// TI - Adaptor proteins as targets for cancer prevention JO - Cancer Prev Res (Phila) VL - 3 UR - https://doi.org/10.1158/1940-6207.CAPR-10-0008 DO - 10.1158/1940-6207.CAPR-10-0008 ID - Yee2010 ER - TY - JOUR AU - Tsyba, L. AU - Nikolaienko, O. AU - Dergai, O. AU - Dergai, M. AU - Novokhatska, O. AU - Skrypkina, I. AU - Rynditch, A. PY - 2011 DA - 2011// TI - Intersectin multidomain adaptor proteins: regulation of functional diversity JO - Gene VL - 473 UR - https://doi.org/10.1016/j.gene.2010.11.016 DO - 10.1016/j.gene.2010.11.016 ID - Tsyba2011 ER - TY - JOUR AU - Okamoto, M. AU - Schoch, S. AU - Sudhof, T. C. PY - 1999 DA - 1999// TI - EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis? JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.26.18446 DO - 10.1074/jbc.274.26.18446 ID - Okamoto1999 ER - TY - JOUR AU - Mohney, R. P. AU - Das, M. AU - Bivona, T. G. AU - Hanes, R. AU - Adams, A. G. AU - Philips, M. R. AU - O'Bryan, J. P. PY - 2003 DA - 2003// TI - Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M303895200 DO - 10.1074/jbc.M303895200 ID - Mohney2003 ER - TY - JOUR AU - O'Bryan, J. P. PY - 2010 DA - 2010// TI - Intersecting pathways in cell biology JO - Sci Signal VL - 3 UR - https://doi.org/10.1126/scisignal.3152re10 DO - 10.1126/scisignal.3152re10 ID - O'Bryan2010 ER - TY - JOUR AU - Predescu, S. A. AU - Predescu, D. N. AU - Timblin, B. K. AU - Stan, R. V. AU - Malik, A. B. PY - 2003 DA - 2003// TI - Intersectin regulates fission and internalization of caveolae in endothelial cells JO - Mol Biol Cell VL - 14 UR - https://doi.org/10.1091/mbc.E03-01-0041 DO - 10.1091/mbc.E03-01-0041 ID - Predescu2003 ER - TY - JOUR AU - Tong, X. K. AU - Hussain, N. K. AU - Adams, A. G. AU - O'Bryan, J. P. AU - McPherson, P. S. PY - 2000 DA - 2000// TI - Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M004096200 DO - 10.1074/jbc.M004096200 ID - Tong2000 ER - TY - JOUR AU - Tong, X. K. AU - Hussain, N. K. AU - Heuvel, E. AU - Kurakin, A. AU - Abi-Jaoude, E. AU - Quinn, C. C. AU - Olson, M. F. AU - Marais, R. AU - Baranes, D. AU - Kay, B. K. AU - McPherson, P. S. PY - 2000 DA - 2000// TI - The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain JO - EMBO J VL - 19 UR - https://doi.org/10.1093/emboj/19.6.1263 DO - 10.1093/emboj/19.6.1263 ID - Tong2000 ER - TY - JOUR AU - Bardita, C. AU - Predescu, D. AU - Justice, M. J. AU - Petrache, I. AU - Predescu, S. PY - 2013 DA - 2013// TI - In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs JO - Apoptosis VL - 18 UR - https://doi.org/10.1007/s10495-012-0762-x DO - 10.1007/s10495-012-0762-x ID - Bardita2013 ER - TY - JOUR AU - Bardita, C. AU - Predescu, D. N. AU - Sha, F. AU - Patel, M. AU - Balaji, G. AU - Predescu, S. A. PY - 2015 DA - 2015// TI - Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5 JO - J Cell Sci VL - 128 UR - https://doi.org/10.1242/jcs.163030 DO - 10.1242/jcs.163030 ID - Bardita2015 ER - TY - JOUR AU - Jeganathan, N. AU - Predescu, D. AU - Zhang, J. AU - Sha, F. AU - Bardita, C. AU - Patel, M. AU - Wood, S. AU - Borgia, J. A. AU - Balk, R. A. AU - Predescu, S. PY - 2016 DA - 2016// TI - Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis JO - Mol Cancer VL - 15 UR - https://doi.org/10.1186/s12943-016-0543-1 DO - 10.1186/s12943-016-0543-1 ID - Jeganathan2016 ER - TY - JOUR AU - Patel, M. AU - Predescu, D. AU - Bardita, C. AU - Chen, J. AU - Jeganathan, N. AU - Pritchard, M. AU - DiBartolo, S. AU - Machado, R. AU - Predescu, S. PY - 2017 DA - 2017// TI - Modulation of Intersectin-1s Lung Expression Induces Obliterative Remodeling and Severe Plexiform Arteriopathy in the Murine Pulmonary Vascular Bed JO - Am J Pathol VL - 187 UR - https://doi.org/10.1016/j.ajpath.2016.11.012 DO - 10.1016/j.ajpath.2016.11.012 ID - Patel2017 ER - TY - JOUR AU - Patel, M. AU - Predescu, D. AU - Tandon, R. AU - Bardita, C. AU - Pogoriler, J. AU - Bhorade, S. AU - Wang, M. AU - Comhair, S. AU - Hemnes, A. R. AU - Chen, J. PY - 2013 DA - 2013// TI - A novel p38 mitogen-activated protein kinase/elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension JO - J Biol Chem VL - 288 UR - https://doi.org/10.1074/jbc.M113.502674 DO - 10.1074/jbc.M113.502674 ID - Patel2013 ER - TY - JOUR AU - Singla, S. AU - Predescu, D. AU - Bardita, C. AU - Wang, M. AU - Zhang, J. AU - Balk, R. A. AU - Predescu, S. PY - 2011 DA - 2011// TI - Pro-inflammatory endothelial cell dysfunction is associated with intersectin-1s down-regulation JO - Respir Res VL - 12 UR - https://doi.org/10.1186/1465-9921-12-46 DO - 10.1186/1465-9921-12-46 ID - Singla2011 ER - TY - JOUR AU - Yamabhai, M. AU - Hoffman, N. G. AU - Hardison, N. L. AU - McPherson, P. S. AU - Castagnoli, L. AU - Cesareni, G. AU - Kay, B. K. PY - 1998 DA - 1998// TI - Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains JO - J Biol Chem VL - 273 UR - https://doi.org/10.1074/jbc.273.47.31401 DO - 10.1074/jbc.273.47.31401 ID - Yamabhai1998 ER - TY - JOUR AU - Kelly, L. E. AU - Phillips, A. M. PY - 2005 DA - 2005// TI - Molecular and genetic characterization of the interactions between the drosophila stoned-B protein and DAP-160 (intersectin) JO - Biochem J VL - 388 UR - https://doi.org/10.1042/BJ20041797 DO - 10.1042/BJ20041797 ID - Kelly2005 ER - TY - JOUR AU - Guipponi, M. AU - Scott, H. S. AU - Chen, H. AU - Schebesta, A. AU - Rossier, C. AU - Antonarakis, S. E. PY - 1998 DA - 1998// TI - Two isoforms of a human intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon JO - Genomics VL - 53 UR - https://doi.org/10.1006/geno.1998.5521 DO - 10.1006/geno.1998.5521 ID - Guipponi1998 ER - TY - JOUR AU - Hunter, M. P. AU - Russo, A. AU - O'Bryan, J. P. PY - 2013 DA - 2013// TI - Emerging roles for Intersectin (ITSN) in regulating signaling and disease pathways JO - Int J Mol Sci VL - 14 UR - https://doi.org/10.3390/ijms14047829 DO - 10.3390/ijms14047829 ID - Hunter2013 ER - TY - JOUR AU - Pucharcos, C. AU - Casas, C. AU - Nadal, M. AU - Estivill, X. AU - Luna, S. PY - 2001 DA - 2001// TI - The human intersectin genes and their spliced variants are differentially expressed JO - Biochim Biophys Acta VL - 1521 UR - https://doi.org/10.1016/S0167-4781(01)00276-7 DO - 10.1016/S0167-4781(01)00276-7 ID - Pucharcos2001 ER - TY - JOUR AU - Novokhatska, O. AU - Dergai, M. AU - Tsyba, L. AU - Skrypkina, I. AU - Filonenko, V. AU - Moreau, J. AU - Rynditch, A. PY - 2013 DA - 2013// TI - Adaptor proteins intersectin 1 and 2 bind similar proline-rich ligands but are differentially recognized by SH2 domain-containing proteins JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0070546 DO - 10.1371/journal.pone.0070546 ID - Novokhatska2013 ER - TY - JOUR AU - Pucharcos, C. AU - Estivill, X. AU - Luna, S. PY - 2000 DA - 2000// TI - Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis JO - FEBS Lett VL - 478 UR - https://doi.org/10.1016/S0014-5793(00)01793-2 DO - 10.1016/S0014-5793(00)01793-2 ID - Pucharcos2000 ER - TY - JOUR AU - Jenna, S. AU - Hussain, N. K. AU - Danek, E. I. AU - Triki, I. AU - Wasiak, S. AU - McPherson, P. S. AU - Lamarche-Vane, N. PY - 2002 DA - 2002// TI - The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M105516200 DO - 10.1074/jbc.M105516200 ID - Jenna2002 ER - TY - JOUR AU - O'Bryan, J. P. AU - Mohney, R. P. AU - Oldham, C. E. PY - 2001 DA - 2001// TI - Mitogenesis and endocytosis: What's at the INTERSECTIoN? JO - Oncogene VL - 20 UR - https://doi.org/10.1038/sj.onc.1204773 DO - 10.1038/sj.onc.1204773 ID - O'Bryan2001 ER - TY - JOUR AU - Hussain, N. K. AU - Yamabhai, M. AU - Ramjaun, A. R. AU - Guy, A. M. AU - Baranes, D. AU - O'Bryan, J. P. AU - Der, C. J. AU - Kay, B. K. AU - McPherson, P. S. PY - 1999 DA - 1999// TI - Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.22.15671 DO - 10.1074/jbc.274.22.15671 ID - Hussain1999 ER - TY - JOUR AU - Kropyvko, S. AU - Gerasymchuk, D. AU - Skrypkina, I. AU - Dergai, M. AU - Dergai, O. AU - Nikolaienko, O. AU - Rynditch, A. AU - Tsyba, L. PY - 2010 DA - 2010// TI - Structural diversity and differential expression of novel human intersectin 1 isoforms JO - Mol Biol Rep VL - 37 UR - https://doi.org/10.1007/s11033-009-9824-8 DO - 10.1007/s11033-009-9824-8 ID - Kropyvko2010 ER - TY - JOUR AU - Martin, N. P. AU - Mohney, R. P. AU - Dunn, S. AU - Das, M. AU - Scappini, E. AU - O'Bryan, J. P. PY - 2006 DA - 2006// TI - Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling JO - Mol Pharmacol VL - 70 UR - https://doi.org/10.1124/mol.106.028274 DO - 10.1124/mol.106.028274 ID - Martin2006 ER - TY - JOUR AU - Tsyba, L. AU - Gryaznova, T. AU - Dergai, O. AU - Dergai, M. AU - Skrypkina, I. AU - Kropyvko, S. AU - Boldyryev, O. AU - Nikolaienko, O. AU - Novokhatska, O. AU - Rynditch, A. PY - 2008 DA - 2008// TI - Alternative splicing affecting the SH3A domain controls the binding properties of intersectin 1 in neurons JO - Biochem Biophys Res Commun VL - 372 UR - https://doi.org/10.1016/j.bbrc.2008.05.156 DO - 10.1016/j.bbrc.2008.05.156 ID - Tsyba2008 ER - TY - JOUR AU - Predescu, S. A. AU - Predescu, D. N. AU - Knezevic, I. AU - Klein, I. K. AU - Malik, A. B. PY - 2007 DA - 2007// TI - Intersectin-1s regulates the mitochondrial apoptotic pathway in endothelial cells JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M608996200 DO - 10.1074/jbc.M608996200 ID - Predescu2007 ER - TY - JOUR AU - Oh, P. AU - McIntosh, D. P. AU - Schnitzer, J. E. PY - 1998 DA - 1998// TI - Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium JO - J Cell Biol VL - 141 UR - https://doi.org/10.1083/jcb.141.1.101 DO - 10.1083/jcb.141.1.101 ID - Oh1998 ER - TY - JOUR AU - Predescu, D. N. AU - Neamu, R. AU - Bardita, C. AU - Wang, M. AU - Predescu, S. A. PY - 2012 DA - 2012// TI - Impaired caveolae function and upregulation of alternative endocytic pathways induced by experimental modulation of intersectin-1s expression in mouse lung endothelium JO - Biochem Res Int VL - 2012 UR - https://doi.org/10.1155/2012/672705 DO - 10.1155/2012/672705 ID - Predescu2012 ER - TY - JOUR AU - Knezevic, I. AU - Predescu, D. AU - Bardita, C. AU - Wang, M. AU - Sharma, T. AU - Keith, B. AU - Neamu, R. AU - Malik, A. B. AU - Predescu, S. PY - 2011 DA - 2011// TI - Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s JO - J Cell Mol Med VL - 15 UR - https://doi.org/10.1111/j.1582-4934.2010.01226.x DO - 10.1111/j.1582-4934.2010.01226.x ID - Knezevic2011 ER - TY - JOUR AU - Hussain, N. K. AU - Jenna, S. AU - Glogauer, M. AU - Quinn, C. C. AU - Wasiak, S. AU - Guipponi, M. AU - Antonarakis, S. E. AU - Kay, B. K. AU - Stossel, T. P. AU - Lamarche-Vane, N. AU - McPherson, P. S. PY - 2001 DA - 2001// TI - Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP JO - Nat Cell Biol VL - 3 UR - https://doi.org/10.1038/ncb1001-927 DO - 10.1038/ncb1001-927 ID - Hussain2001 ER - TY - JOUR AU - Zamanian, J. L. AU - Kelly, R. B. PY - 2003 DA - 2003// TI - Intersectin 1L guanine nucleotide exchange activity is regulated by adjacent src homology 3 domains that are also involved in endocytosis JO - Mol Biol Cell VL - 14 UR - https://doi.org/10.1091/mbc.E02-08-0494 DO - 10.1091/mbc.E02-08-0494 ID - Zamanian2003 ER - TY - JOUR AU - Simanshu, D. K. AU - Nissley, D. V. AU - McCormick, F. PY - 2017 DA - 2017// TI - RAS proteins and their regulators in human disease JO - Cell VL - 170 UR - https://doi.org/10.1016/j.cell.2017.06.009 DO - 10.1016/j.cell.2017.06.009 ID - Simanshu2017 ER - TY - JOUR AU - Hwang, H. S. AU - Hwang, S. G. AU - Yoon, K. W. AU - Yoon, J. H. AU - Roh, K. H. AU - Choi, E. J. PY - 2014 DA - 2014// TI - CIIA negatively regulates the Ras-Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1 JO - J Cell Sci VL - 127 UR - https://doi.org/10.1242/jcs.139931 DO - 10.1242/jcs.139931 ID - Hwang2014 ER - TY - JOUR AU - Pylayeva-Gupta, Y. AU - Grabocka, E. AU - Bar-Sagi, D. PY - 2011 DA - 2011// TI - RAS oncogenes: weaving a tumorigenic web JO - Nat Rev Cancer VL - 11 UR - https://doi.org/10.1038/nrc3106 DO - 10.1038/nrc3106 ID - Pylayeva-Gupta2011 ER - TY - JOUR AU - Heasman, S. J. AU - Ridley, A. J. PY - 2008 DA - 2008// TI - Mammalian rho GTPases: new insights into their functions from in vivo studies JO - Nat Rev Mol Cell Biol VL - 9 UR - https://doi.org/10.1038/nrm2476 DO - 10.1038/nrm2476 ID - Heasman2008 ER - TY - JOUR AU - Hwang, H. S. AU - Hwang, S. G. AU - Cho, J. H. AU - Chae, J. S. AU - Yoon, K. W. AU - Cho, S. G. AU - Choi, E. J. PY - 2011 DA - 2011// TI - CIIA functions as a molecular switch for the Rac1-specific GEF activity of SOS1 JO - J Cell Biol VL - 195 UR - https://doi.org/10.1083/jcb.201106138 DO - 10.1083/jcb.201106138 ID - Hwang2011 ER - TY - JOUR AU - Innocenti, M. AU - Frittoli, E. AU - Ponzanelli, I. AU - Falck, J. R. AU - Brachmann, S. M. AU - Fiore, P. P. AU - Scita, G. PY - 2003 DA - 2003// TI - Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1 JO - J Cell Biol VL - 160 UR - https://doi.org/10.1083/jcb.200206079 DO - 10.1083/jcb.200206079 ID - Innocenti2003 ER - TY - JOUR AU - Innocenti, M. AU - Tenca, P. AU - Frittoli, E. AU - Faretta, M. AU - Tocchetti, A. AU - Fiore, P. P. AU - Scita, G. PY - 2002 DA - 2002// TI - Mechanisms through which Sos-1 coordinates the activation of Ras and Rac JO - J Cell Biol VL - 156 UR - https://doi.org/10.1083/jcb.200108035 DO - 10.1083/jcb.200108035 ID - Innocenti2002 ER - TY - JOUR AU - Primeau, M. AU - Ben Djoudi Ouadda, A. AU - Lamarche-Vane, N. PY - 2011 DA - 2011// TI - Cdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motif JO - FEBS Lett VL - 585 UR - https://doi.org/10.1016/j.febslet.2011.02.022 DO - 10.1016/j.febslet.2011.02.022 ID - Primeau2011 ER - TY - JOUR AU - Russo, A. AU - O'Bryan, J. P. PY - 2012 DA - 2012// TI - Intersectin 1 is required for neuroblastoma tumorigenesis JO - Oncogene VL - 31 UR - https://doi.org/10.1038/onc.2011.643 DO - 10.1038/onc.2011.643 ID - Russo2012 ER - TY - JOUR AU - Scita, G. AU - Tenca, P. AU - Areces, L. B. AU - Tocchetti, A. AU - Frittoli, E. AU - Giardina, G. AU - Ponzanelli, I. AU - Sini, P. AU - Innocenti, M. AU - Fiore, P. P. PY - 2001 DA - 2001// TI - An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine JO - J Cell Biol VL - 154 UR - https://doi.org/10.1083/jcb.200103146 DO - 10.1083/jcb.200103146 ID - Scita2001 ER - TY - JOUR AU - Schmidt, M. H. AU - Dikic, I. PY - 2005 DA - 2005// TI - The Cbl interactome and its functions JO - Nat Rev Mol Cell Biol VL - 6 UR - https://doi.org/10.1038/nrm1762 DO - 10.1038/nrm1762 ID - Schmidt2005 ER - TY - JOUR AU - Parri, M. AU - Chiarugi, P. PY - 2010 DA - 2010// TI - Rac and rho GTPases in cancer cell motility control JO - Cell Commun Signal VL - 8 UR - https://doi.org/10.1186/1478-811X-8-23 DO - 10.1186/1478-811X-8-23 ID - Parri2010 ER - TY - JOUR AU - Sander, E. E. AU - Klooster, J. P. AU - Delft, S. AU - Kammen, R. A. AU - Collard, J. G. PY - 1999 DA - 1999// TI - Rac downregulates rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior JO - J Cell Biol VL - 147 UR - https://doi.org/10.1083/jcb.147.5.1009 DO - 10.1083/jcb.147.5.1009 ID - Sander1999 ER - TY - JOUR AU - McPherson, P. S. AU - Kay, B. K. AU - Hussain, N. K. PY - 2001 DA - 2001// TI - Signaling on the endocytic pathway JO - Traffic VL - 2 UR - https://doi.org/10.1034/j.1600-0854.2001.002006375.x DO - 10.1034/j.1600-0854.2001.002006375.x ID - McPherson2001 ER - TY - JOUR AU - Okur, M. N. AU - Ooi, J. AU - Fong, C. W. AU - Martinez, N. AU - Garcia-Dominguez, C. AU - Rojas, J. M. AU - Guy, G. AU - O'Bryan, J. P. PY - 2012 DA - 2012// TI - Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction JO - Mol Cell Biol VL - 32 UR - https://doi.org/10.1128/MCB.05647-11 DO - 10.1128/MCB.05647-11 ID - Okur2012 ER - TY - JOUR AU - Okur, M. N. AU - Russo, A. AU - O'Bryan, J. P. PY - 2014 DA - 2014// TI - Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase JO - Mol Cell Biol VL - 34 UR - https://doi.org/10.1128/MCB.00850-13 DO - 10.1128/MCB.00850-13 ID - Okur2014 ER - TY - JOUR AU - Wang, J. B. AU - Wu, W. J. AU - Cerione, R. A. PY - 2005 DA - 2005// TI - Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M414375200 DO - 10.1074/jbc.M414375200 ID - Wang2005 ER - TY - JOUR AU - Patja, K. AU - Pukkala, E. AU - Sund, R. AU - Iivanainen, M. AU - Kaski, M. PY - 2006 DA - 2006// TI - Cancer incidence of persons with down syndrome in Finland: a population-based study JO - Int J Cancer VL - 118 UR - https://doi.org/10.1002/ijc.21518 DO - 10.1002/ijc.21518 ID - Patja2006 ER - TY - JOUR AU - Liu, C. AU - Belichenko, P. V. AU - Zhang, L. AU - Fu, D. AU - Kleschevnikov, A. M. AU - Baldini, A. AU - Antonarakis, S. E. AU - Mobley, W. C. AU - Yu, Y. E. PY - 2011 DA - 2011// TI - Mouse models for down syndrome-associated developmental cognitive disabilities JO - Dev Neurosci VL - 33 UR - https://doi.org/10.1159/000329422 DO - 10.1159/000329422 ID - Liu2011 ER - TY - STD TI - The Human Protein Atlas [http://www.proteinatlas.org/ENSG00000205726-ITSN1/pathology/]. Accessed 20 Aug 2017. UR - http://www.proteinatlas.org/ENSG00000205726-ITSN1/pathology ID - ref55 ER - TY - JOUR AU - Gu, F. AU - Zhang, H. AU - Qin, F. AU - Liu, X. AU - Li, W. AU - Fu, L. AU - Ying, G. AU - Li, B. AU - Zhang, M. AU - Ma, Y. PY - 2015 DA - 2015// TI - Intersectin1-s, A multidomain adapter protein, Is essential for malignant glioma proliferation JO - Glia VL - 63 UR - https://doi.org/10.1002/glia.22830 DO - 10.1002/glia.22830 ID - Gu2015 ER - TY - JOUR AU - Ma, Y. AU - Wang, B. AU - Li, W. AU - Ying, G. AU - Fu, L. AU - Niu, R. AU - Gu, F. PY - 2010 DA - 2010// TI - Reduction of intersectin1-s induced apoptosis of human glioblastoma cells JO - Brain Res VL - 1351 UR - https://doi.org/10.1016/j.brainres.2010.05.028 DO - 10.1016/j.brainres.2010.05.028 ID - Ma2010 ER - TY - JOUR AU - Stamm, S. AU - Ben-Ari, S. AU - Rafalska, I. AU - Tang, Y. AU - Zhang, Z. AU - Toiber, D. AU - Thanaraj, T. A. AU - Soreq, H. PY - 2005 DA - 2005// TI - Function of alternative splicing JO - Gene VL - 344 UR - https://doi.org/10.1016/j.gene.2004.10.022 DO - 10.1016/j.gene.2004.10.022 ID - Stamm2005 ER - TY - JOUR AU - Keating, D. J. AU - Chen, C. AU - Pritchard, M. A. PY - 2006 DA - 2006// TI - Alzheimer's disease and endocytic dysfunction: clues from the down syndrome-related proteins, DSCR1 and ITSN1 JO - Ageing Res Rev VL - 5 UR - https://doi.org/10.1016/j.arr.2005.11.001 DO - 10.1016/j.arr.2005.11.001 ID - Keating2006 ER - TY - JOUR AU - Kong, X. D. AU - Liu, N. AU - Xu, X. J. PY - 2014 DA - 2014// TI - Bioinformatics analysis of biomarkers and transcriptional factor motifs in down syndrome JO - Braz J Med Biol Res VL - 47 UR - https://doi.org/10.1590/1414-431X20143792 DO - 10.1590/1414-431X20143792 ID - Kong2014 ER - TY - JOUR AU - Sharpe, D. A. AU - Dixon, K. AU - Moghissi, K. PY - 1996 DA - 1996// TI - Endoscopic laser treatment for tracheal obstruction JO - Eur J Cardiothorac Surg VL - 10 UR - https://doi.org/10.1016/S1010-7940(96)80331-9 DO - 10.1016/S1010-7940(96)80331-9 ID - Sharpe1996 ER - TY - JOUR AU - Dergai, M. AU - Skrypkina, I. AU - Dergai, O. AU - Tsyba, L. AU - Novokhatska, O. AU - Filonenko, V. AU - Drobot, L. AU - Rynditch, A. PY - 2011 DA - 2011// TI - Identification and characterization of a novel mammalian isoform of the endocytic adaptor ITSN1 JO - Gene VL - 485 UR - https://doi.org/10.1016/j.gene.2011.06.021 DO - 10.1016/j.gene.2011.06.021 ID - Dergai2011 ER - TY - JOUR AU - Dergai, M. AU - Tsyba, L. AU - Dergai, O. AU - Zlatskii, I. AU - Skrypkina, I. AU - Kovalenko, V. AU - Rynditch, A. PY - 2010 DA - 2010// TI - Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface JO - Biochem Biophys Res Commun VL - 399 UR - https://doi.org/10.1016/j.bbrc.2010.07.080 DO - 10.1016/j.bbrc.2010.07.080 ID - Dergai2010 ER - TY - JOUR AU - Kissil, J. L. AU - Walmsley, M. J. AU - Hanlon, L. AU - Haigis, K. M. AU - Bender Kim, C. F. AU - Sweet-Cordero, A. AU - Eckman, M. S. AU - Tuveson, D. A. AU - Capobianco, A. J. AU - Tybulewicz, V. L. AU - Jacks, T. PY - 2007 DA - 2007// TI - Requirement for Rac1 in a K-ras induced lung cancer in the mouse JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-07-2300 DO - 10.1158/0008-5472.CAN-07-2300 ID - Kissil2007 ER - TY - JOUR AU - Archibald, A. AU - Mihai, C. AU - Macara, I. G. AU - McCaffrey, L. PY - 2015 DA - 2015// TI - Oncogenic suppression of apoptosis uncovers a Rac1/JNK proliferation pathway activated by loss of Par3 JO - Oncogene VL - 34 UR - https://doi.org/10.1038/onc.2014.242 DO - 10.1038/onc.2014.242 ID - Archibald2015 ER - TY - JOUR AU - Wang, H. AU - Teh, M. T. AU - Ji, Y. AU - Patel, V. AU - Firouzabadian, S. AU - Patel, A. A. AU - Gutkind, J. S. AU - Yeudall, W. A. PY - 2010 DA - 2010// TI - EPS8 upregulates FOXM1 expression, enhancing cell growth and motility JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgq058 DO - 10.1093/carcin/bgq058 ID - Wang2010 ER - TY - JOUR AU - Henson, P. M. AU - Tuder, R. M. PY - 2008 DA - 2008// TI - Apoptosis in the lung: induction, clearance and detection JO - Am J Physiol Lung Cell Mol Physiol VL - 294 UR - https://doi.org/10.1152/ajplung.00320.2007 DO - 10.1152/ajplung.00320.2007 ID - Henson2008 ER - TY - JOUR AU - Predescu, D. N. AU - Bardita, C. AU - Tandon, R. AU - Predescu, S. A. PY - 2013 DA - 2013// TI - Intersectin-1s: an important regulator of cellular and molecular pathways in lung injury JO - Pulm Circ VL - 3 UR - https://doi.org/10.1086/674439 DO - 10.1086/674439 ID - Predescu2013 ER - TY - JOUR AU - Schmidt, E. P. AU - Tuder, R. M. PY - 2010 DA - 2010// TI - Role of apoptosis in amplifying inflammatory responses in lung diseases JO - J Cell Death VL - 2010 ID - Schmidt2010 ER - TY - JOUR AU - Fiore, P. P. AU - Camilli, P. PY - 2001 DA - 2001// TI - Endocytosis and signaling. An inseparable partnership JO - Cell VL - 106 UR - https://doi.org/10.1016/S0092-8674(01)00428-7 DO - 10.1016/S0092-8674(01)00428-7 ID - Fiore2001 ER - TY - JOUR AU - Crosby, L. M. AU - Waters, C. M. PY - 2010 DA - 2010// TI - Epithelial repair mechanisms in the lung JO - Am J Physiol Lung Cell Mol Physiol VL - 298 UR - https://doi.org/10.1152/ajplung.00361.2009 DO - 10.1152/ajplung.00361.2009 ID - Crosby2010 ER - TY - JOUR AU - Derynck, R. AU - Zhang, Y. E. PY - 2003 DA - 2003// TI - Smad-dependent and Smad-independent pathways in TGF-beta family signalling JO - Nature VL - 425 UR - https://doi.org/10.1038/nature02006 DO - 10.1038/nature02006 ID - Derynck2003 ER - TY - JOUR AU - Predescu, S. AU - Bardita, C. AU - Predescu, D. PY - 2015 DA - 2015// TI - New insights into the functions of intersectin-1s JO - Commun Integr Biol VL - 8 UR - https://doi.org/10.1080/19420889.2015.1034400 DO - 10.1080/19420889.2015.1034400 ID - Predescu2015 ER - TY - JOUR AU - Guglielmo, G. M. AU - Roy, C. AU - Goodfellow, A. F. AU - Wrana, J. L. PY - 2003 DA - 2003// TI - Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover JO - Nat Cell Biol VL - 5 UR - https://doi.org/10.1038/ncb975 DO - 10.1038/ncb975 ID - Guglielmo2003 ER - TY - JOUR AU - McVey, M. AU - Tabuchi, A. AU - Kuebler, W. M. PY - 2012 DA - 2012// TI - Microparticles and acute lung injury JO - Am J Physiol Lung Cell Mol Physiol VL - 303 UR - https://doi.org/10.1152/ajplung.00354.2011 DO - 10.1152/ajplung.00354.2011 ID - McVey2012 ER - TY - JOUR AU - Predescu, S. AU - Shah, T. G. AU - Qin, S. AU - Bardita, C. AU - Jeganathan, N. AU - Balk, R. AU - Predescu, D. PY - 2017 DA - 2017// TI - Two Runx1 isoforms determine the outcome in Ards JO - AJRCCM VL - 195 ID - Predescu2017 ER - TY - JOUR AU - Lacroix, R. AU - Judicone, C. AU - Mooberry, M. AU - Boucekine, M. AU - Key, N. S. AU - Dignat-George, F. PY - 2013 DA - 2013// TI - Standardization of pre-analytical variables in plasma microparticle determination: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop JO - J Thromb Haemost. VL - 11 UR - https://doi.org/10.1111/jth.12207 DO - 10.1111/jth.12207 ID - Lacroix2013 ER - TY - JOUR AU - Chen, J. AU - Li, C. AU - Chen, L. PY - 2015 DA - 2015// TI - The role of microvesicles derived from Mesenchymal stem cells in lung diseases JO - Biomed Res Int VL - 2015 ID - Chen2015 ER - TY - JOUR AU - Hall, J. B. AU - Kress, J. P. PY - 2011 DA - 2011// TI - The burden of functional recovery from ARDS JO - N Engl J Med VL - 364 UR - https://doi.org/10.1056/NEJMe1101057 DO - 10.1056/NEJMe1101057 ID - Hall2011 ER - TY - JOUR AU - Humbert, M. AU - Morrell, N. W. AU - Archer, S. L. AU - Stenmark, K. R. AU - MacLean, M. R. AU - Lang, I. M. AU - Christman, B. W. AU - Weir, E. K. AU - Eickelberg, O. AU - Voelkel, N. F. AU - Rabinovitch, M. PY - 2004 DA - 2004// TI - Cellular and molecular pathobiology of pulmonary arterial hypertension JO - J Am Coll Cardiol VL - 43 UR - https://doi.org/10.1016/j.jacc.2004.02.029 DO - 10.1016/j.jacc.2004.02.029 ID - Humbert2004 ER - TY - JOUR AU - Schermuly, R. T. AU - Ghofrani, H. A. AU - Wilkins, M. R. AU - Grimminger, F. PY - 2011 DA - 2011// TI - Mechanisms of disease: pulmonary arterial hypertension JO - Nat Rev Cardiol VL - 8 UR - https://doi.org/10.1038/nrcardio.2011.87 DO - 10.1038/nrcardio.2011.87 ID - Schermuly2011 ER - TY - JOUR AU - Tuder, R. M. AU - Marecki, J. C. AU - Richter, A. AU - Fijalkowska, I. AU - Flores, S. PY - 2007 DA - 2007// TI - Pathology of pulmonary hypertension JO - Clin Chest Med VL - 28 UR - https://doi.org/10.1016/j.ccm.2006.11.010 DO - 10.1016/j.ccm.2006.11.010 ID - Tuder2007 ER - TY - JOUR AU - Buzza, M. S. AU - Hirst, C. E. AU - Bird, C. H. AU - Hosking, P. AU - McKendrick, J. AU - Bird, P. I. PY - 2001 DA - 2001// TI - The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses JO - Cell Immunol VL - 210 UR - https://doi.org/10.1006/cimm.2001.1806 DO - 10.1006/cimm.2001.1806 ID - Buzza2001 ER - TY - JOUR AU - Loeb, C. R. AU - Harris, J. L. AU - Craik, C. S. PY - 2006 DA - 2006// TI - Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M604544200 DO - 10.1074/jbc.M604544200 ID - Loeb2006 ER - TY - JOUR AU - Jeffery, T. K. AU - Morrell, N. W. PY - 2002 DA - 2002// TI - Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension JO - Prog Cardiovasc Dis VL - 45 UR - https://doi.org/10.1053/pcad.2002.130041 DO - 10.1053/pcad.2002.130041 ID - Jeffery2002 ER - TY - JOUR AU - Mortimer, H. J. AU - Peacock, A. J. AU - Kirk, A. AU - Welsh, D. J. PY - 2007 DA - 2007// TI - p38 MAP kinase: essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation JO - Pulm Pharmacol Ther VL - 20 UR - https://doi.org/10.1016/j.pupt.2006.08.007 DO - 10.1016/j.pupt.2006.08.007 ID - Mortimer2007 ER - TY - JOUR AU - Beer, T. AU - Carter, R. E. AU - Lobel-Rice, K. E. AU - Sorkin, A. AU - Overduin, M. PY - 1998 DA - 1998// TI - Structure and Asn-pro-Phe binding pocket of the Eps15 homology domain JO - Science VL - 281 UR - https://doi.org/10.1126/science.281.5381.1357 DO - 10.1126/science.281.5381.1357 ID - Beer1998 ER - TY - STD TI - Predescu S PM, Chen JDP. Targeted delivery of the NH2-terminal fragment of intersectin-1s triggers formation of complex plexiform lesions in mouse lungs. AJRCCM. 2015;191:A1936. ID - ref88 ER -