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Table 3 Comparison of patients with AECOPD with and without ECAC

From: Expiratory central airway collapse in stable COPD and during exacerbations

 

No ECAC

(n = 39)

ECAC

(n = 25)

P value

Age, years

68 ± 12.5

73.4 ± 9.2

0.069

Gender (female:male)

15:24

9:16

1.0

Body mass index (kg/m2)

26.7 ± 7.4

25.6 ± 5

0.613

FEV1 (% predicted)

48.4 ± 24.7

47.0 ± 21.2

0.843

FVC (% predicted)

75.3 ± 20.4

70.8 ± 20.8

0.488

FEV1/FVC (% predicted)

47.0 ± 18.2

48.7 ± 14.1

0.750

Bronchodilator response

8.0 ± 8.5

4 ± 8

0.162

Pack years smoked

60.6 ± 54.7

63.3 ± 58.8

0.880

TLCO (% predicted)

42.2 ± 18.2

48.1 ± 19.7

0.357

Length of stay (days)

4.4 ± 3.3

5.7 ± 6

0.267

Baseline mMRC dyspnea score

2.2 ± 1.2

2.4 ± 1.2

0.404

Admission mMRC dyspnea score

3.7 ± 0.5

3.7 ± 0.4

0.766

BAP65 (class - n)

I 6

II 17

III 12

IV 2

I 1

II 8

III 9

IV 5

0.172

Oral prednisolone at admission (mg/day)

3.9 ± 10.5

1.0 ± 2.2

0.201

Days on noninvasive ventilation

0.3 ± 0.5

2.2 ± 2.6

0.197

Need for noninvasive ventilation (n)

4

4

1.0

Death at 30 days (n)

1

0

1.0

Hospital admissions in prior 12 months

0.6 ± 1.3

1.0 ± 1.7

0.342

TBM

Sabre 3

Concentric 2

Crescentic 1

Sabre 1

Concentric 3

Crescentic 0

0.732

  1. ECAC expiratory central airway collapse; FEV 1 forced expiratory volume in one second; FVC forced vital capacity; TLCO transfer capacity for carbon monoxide; mMRC modified Medical Research Council dyspnoea score; BAP65 score – calculated per Shorr et al. [15]. TBM tracheobronchomalacia. Data are mean ± SD unless otherwise specified. P values are for independent samples t-test or Fisher’s exact test