Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients

Respiratory Research

Table 2 Mean number of sequences per sample constituting the 15 taxa^a found in significantly different amounts in induced and spontaneous sputum from COPD patients with and without respect to disease state

	All samples			Exacerbation			Stable state
Taxonomy^b	Induced	Spontaneous	p^c	Induced	Spontaneous	p^c	Induced	Spontaneous	p^c
f_Prevotellaceae;g_Prevotella	2499.2	1760.3	<0.001	2633.1	1817.1	<0.001	2349.5	1763.0	<0.001
f_Pasteurellaceae;g_Haemophilus	1471.9	2440.3	<0.001	1308.2	2356.6	<0.001	1957.7	2859.8	<0.001
f_Moraxellaceae;g_Moraxella	259.2	542.3	<0.001	234.4	456.5	<0.001	353.9	798.0	0.001
f_Veillonellaceae;g_Veillonella	1488.3	1170.8	<0.001	1618.8	1173.1	<0.001
f_Veillonellaceae;g_Megasphaera	179.9	100.0	<0.001	201.9	111.5	<0.001	134.8	79.4	0.01
f_Corynebacteriaceae;g_Corynebacterium	44.9	12.0	<0.001	60.3	14.9	<0.001
f_Oxalobacteraceae;g_Ralstonia				423.3	604.7	<0.001	331.8	213.3	<0.001
f_Comamonadaceae;g_Curvibacter				518.7	713.0	<0.001	430.7	269.5	<0.001
f_Leptotrichiaceae;g_Leptotrichia				171.8	95.2	<0.001
f_Neisseriaceae;g_Neisseria							344.5	149.8	<0.001
f_Gemellaceae;g_Gemella							84.9	16.5	<0.001
f_Gemellaceae;g_							452.7	273.6	<0.001
f_Neisseriaceae;g_							79.5	17.5	<0.001
f_Leptotrichiaceae;g_Leptotrichia							123.6	217.6	<0.001
f_Actinomycetaceae;g_Actinomyces							350.1	256.0	0.001

^aRarefied OTU-tables: Sequences/Sample = 18,250 for All samples and Exacerbations, for Stable state: 19,743
^bGreenGenes Level 6: f_ = Name of family level g_ = Name of genus level. One hundred six different taxa in total
^clog-likelihood ratio test, Bonferroni corrected due to multiple comparisons

ISSN: 1465-993X