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Table 3 A comparison of survival between ex-smokers and non-smokers in the step-by-step multivariate models

From: Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis

  HR 95% CI p-value
Univariate
 Ex-smoker Reference   
 Non-smoker 0.64 0.42 – 0.97 0.037
Model containing DLco%
 Ex-smoker Reference   
 Non-smoker 0.79 0.50 – 1.24 0.306
 Dlco% 0.97 0.95 – 0.98 <0.001
Model containing CPI
 Ex-smoker Reference   
 Non-smoker 0.75 0.48 – 1.17 0.197
 CPI 1.04 1.02 – 1.06 <0.001
Model containing DLco % and age
 Ex-smoker Reference   
 Non-smoker 0.82 0.52 – 1.27 0.371
 Dlco% 0.96 0.95 – 0.98 <0.001
 Age at diagnosis 1.05 1.02 – 1.08 0.001
Model containing CPI and age
 Ex-smoker Reference   
 Non-smoker 0.79 0.51 – 1.23 0.292
 CPI 1.05 1.03 – 1.07 <0.001
 Age at diagnosis 1.06 1.03 – 1.09 <0.001
Model containing DLco %, age and gender
 Ex-smoker Reference   
 Non-smoker 1.32 0.76 – 2.30 0.324
 Dlco% 0.96 0.95 – 0.98 <0.001
 Age at diagnosis 1.06 1.03 – 1.09 <0.001
 Gender - female Reference   
 male 2.35 1.24 – 4.45 0.009
Model containing CPI, age and gender
 Ex-smoker Reference   
 Non-smoker 1.22 0.71 – 2.10 0.472
 CPI 1.05 1.03 – 1.07 <0.001
 Age at diagnosis 1.07 1.04 – 1.10 <0.001
 Gender - female Reference   
 male 2.22 1.18 – 4.18 0.013
  1. HR hazard ratio, CI confidence interval, DLco diffusion capacity of carbon monoxide, CPI composite physiologic index