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Table 2 A comparison of survival between ex-smokers and current smokers in the step-by-step multivariate models

From: Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis

  HR 95% CI p-value
Univariate
 Ex-smoker Reference   
 Current smoker 0.52 0.29 – 0.95 0.033
Model containing DLco%
 Ex-smoker Reference   
 Current smoker 0.60 0.33 – 1.10 0.098
 Dlco% 0.97 0.96 – 0.99 0.001
Model containing CPI
 Ex-smoker Reference   
 Current smoker 0.62 0.34 – 1.14 0.126
 CPI 1.03 1.01 – 1.05 0.001
Model containing DLco % and age
 Ex-smoker Reference   
 Current smoker 1.32 062 – 2.72 0.472
 Dlco% 0.97 0.95 – 0.98 <0.001
 Age at diagnosis 1.06 1.02 – 1.10 0.001
Model containing CPI and age
 Ex-smoker Reference   
 Current smoker 1.63 0.75 – 3.54 0.217
 CPI 1.05 1.02 – 1.07 < 0.001
 Age at diagnosis 1.07 1.03 – 1.12 <0.001
Model containing DLco %, age and gender
 Ex-smoker Reference   
 Current smoker 1.32 063 – 2.80 0.465
 Dlco% 0.97 0.95 – 0.99 <0.001
 Age at diagnosis 1.06 1.03 – 1.10 0.001
 Gender - female Reference   
 male 1.10 0.45 – 2.69 0.831
Model containing CPI, age and gender
 Ex-smoker Reference   
 Current smoker 1.66 0.76 – 3.64 0.203
 CPI 1.05 1.02 – 1.07 <0.001
 Age at diagnosis 1.07 1.03 – 1.12 <0.001
 Gender - female Reference   
 male 1.22 0.51 – 2.94 0.657
  1. HR hazard ratio, CI confidence interval, DLco diffusion capacity of carbon monoxide, CPI composite physiologic index