Fig. 1

miR-181c expression was decreased in the lung tissues of COPD patients and CS-exposed mice. a The relative expression levels of miR-181c were examined by qRT-PCR in lung tissues of 8 never smokers, 8 smokers without COPD and 18 COPD patients. b The expression levels of miR-181c in HBECs 24 h after CSE exposure. c miR-181c expression was tested in lungs of mice exposed to air or CS for 4 or 24 weeks. *p < 0.05, **p < 0.01