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Table 1 MHCII expression in AT2 cells and the proportion of AT2 cells in total cells and P1 cells from different strains and ages of mice

From: Fraction of MHCII and EpCAM expression characterizes distal lung epithelial cells for alveolar type 2 cell isolation

Strain

Age

The yield of single cell suspension (×106/ lung)

proSP-C+ cells/Live single cells (%)

MHCII+ cells/proSP-C+ cells (%)

proSP-C+ cells/P1 cells (%)

 

3-wk.-old

4.3 ± 0.6

25.2 ± 1.7

99.2 ± 0.2

97.2 ± 0.2

C57BL/6 J

9-wk.-old

8.1 ± 0.4

34.5 ± 1.9

99.0 ± 0.2

97.9 ± 0.4

 

1-yr.-old

9.7 ± 0.8

31.1 ± 1.2

99.2 ± 0.2

97.4 ± 0.3

BALB/c

9-wk.-old

8.2 ± 0.4

32.0 ± 3.5

99.6 ± 0.0

97.7 ± 0.5

FVB/N

9-wk.-old

8.7 ± 0.7

33.3 ± 0.8

99.1 ± 0.2

97.6 ± 0.4

  1. The values are expressed as the means ± SE (n = 3/group). MHCII, major histocompatibility complex class II; proSP-C, pro-surfactant protein C
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Respiratory Research

ISSN: 1465-993X

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