Table 2 Extracellular region is an enriched gene ontology category (GO: 0005576) associated with the significantly decreased transcripts in JF1/MsJ vs C3H/HeJ mouse lung at embryonic day 18 (E18) and postnatal day 70 (P70)
Gene | Gene symbol | Entrez ID | Fold Difference |
|---|---|---|---|
E18 decreased transcripts of GO term extracellular region; Enrichment Score = 2.83; p = 0.0005 | |||
Chemokine (C-X-C motif) ligand 15 | Cxcl15 | 20,309 | −14.6 |
Hemolytic complement | Hc | 15,139 | −8.61 |
Kallikrein 1-related peptidase b21 | Klk1b21 | 16,616 | −8.25 |
Surfactant associated protein A1 | Sftpa1 | 20,387 | −3.80 |
Collagen, type XXVIII, alpha 1 | Col28a1 | 213,945 | −3.15 |
Paraoxonase 3 | Pon3 | 269,823 | −2.96 |
Ceruloplasmin | Cp | 12,870 | −2.95 |
Neuron-derived neurotrophic factor | Ndnf | 68,169 | −2.41 |
Fibroblast growth factor 1 | Fgf1 | 14,164 | −2.21 |
EGF-like, fibronectin type III and laminin G domains | Egflam | 268,780 | −2.13 |
Transferrin | Trf | 22,041 | −2.12 |
Interleukin 33 | Il33 | 77,125 | −2.04 |
P70 decreased transcripts of GO term extracellular region; Enrichment Score = 4.18; p = 0.04 | |||
Hemolytic complement | Hc | 15,139 | −27.88 |
Chitinase 3-like 3 | Chi3l3 | 12,655 | −15.93 |
Kallikrein 1-related peptidase b21 | Klk1b21 | 16,616 | −11.92 |
Hepcidin antimicrobial peptide | Hamp | 84,506 | −4.87 |
Chemokine (C-C motif) ligand 6 | Ccl6 | 20,305 | −3.92 |
Matrix metallopeptidase 3 | Mmp3 | 17,392 | −3.62 |
Insulin-like growth factor binding protein 6 | Igfbp6 | 16,012 | −2.83 |
Collagen, type XXVIII, alpha 1 | Col28a1 | 213,945 | −2.76 |
Angiopoietin-like 7 | Angptl7 | 654,812 | −2.72 |
Leptin receptor | Lepr | 16,847 | −2.28 |
Chitinase, acidic | Chia | 81,600 | −2.26 |
Oxidized low density lipoprotein (lectin-like) receptor 1 | Olr1 | 108,078 | −2.21 |
Coagulation factor VII | F7 | 14,068 | −2.18 |
Paraoxonase 3 | Pon3 | 269,823 | −2.18 |
Plasminogen activator, tissue | Plat | 18,791 | −2.10 |
Secreted Ly6/Plaur domain containing 1 | Slurp1 | 57,277 | −2.02 |