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Fig. 1 | Respiratory Research

Fig. 1

From: The effect of glycopyrronium and indacaterol, as monotherapy and in combination, on the methacholine dose-response curve of mild asthmatics: a randomized three-way crossover study

Fig. 1

Mean non-asthmatic (control), baseline and post-treatment methacholine dose-response curves at 1 h (a), 24 h (b), and 48 h (c) are shown. The methacholine concentration causing a minimum 20% fall in FEV1 at baseline is designated as zero on the x-axis (i.e. corresponds to the final data point on baseline curves). Mean responses below (three) and above (five) comprise the post-treatment dose-response curves. Only data points with at least n = 8 are included. The sample size for each curve is: n = 15 for LAMA, n = 16 for uLABA, and n = 14 for combo

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