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Table 2 Cut-off values for referral to the home ventilation services

From: The predictive value of respiratory function tests for non-invasive ventilation in amyotrophic lateral sclerosis

 

Suggested values

Guideline values [9, 15, 27]

 

Cut-off value

Sensitivity

Specificity

Cut-off value

Sensitivity

Specificity

FVC

95 (77–104)

85

22

70

65

50

PCF

386 (356–472)

88

36

300

33

67

MIP

67 (52–74)

85

27

60

82

35

MEP

74 (66–90)

85

38

60

68

56

SNIP

45 (41–59)

87

40

40

71

50

  1. Cut-off values are presented as value (95% CI). The sensitivity and specificity are calculated with an ROC curve analysis. ALS Amyotrophic Lateral Sclerosis, HVS Home Ventilation Services, NIV Non-invasive ventilation, FVC Forced Vital Capacity (% predicted value), PCF Peak Cough Flow (L/min.), MIP and MEP Maximum Inspiratory and Expiratory Pressure (cm H2O), SNIP Sniff Nasal Inspiratory Pressure (cm H2O)