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Table 2 Cut-off values for referral to the home ventilation services

From: The predictive value of respiratory function tests for non-invasive ventilation in amyotrophic lateral sclerosis

  Suggested values Guideline values [9, 15, 27]
  Cut-off value Sensitivity Specificity Cut-off value Sensitivity Specificity
FVC 95 (77–104) 85 22 70 65 50
PCF 386 (356–472) 88 36 300 33 67
MIP 67 (52–74) 85 27 60 82 35
MEP 74 (66–90) 85 38 60 68 56
SNIP 45 (41–59) 87 40 40 71 50
  1. Cut-off values are presented as value (95% CI). The sensitivity and specificity are calculated with an ROC curve analysis. ALS Amyotrophic Lateral Sclerosis, HVS Home Ventilation Services, NIV Non-invasive ventilation, FVC Forced Vital Capacity (% predicted value), PCF Peak Cough Flow (L/min.), MIP and MEP Maximum Inspiratory and Expiratory Pressure (cm H2O), SNIP Sniff Nasal Inspiratory Pressure (cm H2O)