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Table 1 Level of circulating and mature fibrocytes according to disease group

From: Fibrocyte measurement in peripheral blood correlates with number of cultured mature fibrocytes in vitro and is a potential biomarker for interstitial lung disease in Rheumatoid Arthritis

 

Control

RA

Severe asthma

IPF/NSIP

RA-ILD

 

n = 10

n = 10

n = 10

n = 5/n = 4

n = 10

Flow cytometry

 

 2003CD45+CD34+CD11b+ cells/μL

 median (P25-P75)

1.69

(0.94–2.89)

3.84

(2.52–6.25)

4.88

(3.44–6.16)

6.13

(3.58–7.93)

6.45

(5.89–9.44)

Cultured mononuclear cells

 

 Fibrocytes/105 monocytes

 median (P25-P75)

887

(331–1590)

4140

(3069–5557)

4634

(3213–6881)

3897

(2570–5809)

6266

(3946–7437)

  1. Cells presented in counted numbers and as medians with 25th- and 75th percentiles in brackets. Culture of mononuclear cells failed from 4 patient samples (2 Severe Asthma, 1 ILD, 1 RA-ILD)