N (%) | mean (SD) | Delta 95% CI p value | mean (SD) | Delta 95% CI p value | mean (SD) | Delta 95% CI p value | mean (SD) | Delta 95% CI p value | |
---|---|---|---|---|---|---|---|---|---|
Antiinflammatory therapya | |||||||||
No | 426 (57.8%) | 63.6 (19.0) | (ref) | 14.9 (5.9) | (ref) | 43.9 (19.9) | (ref) | 40.0 (27.9) | (ref) |
Yes | 311 (42.2%) | 55.4 (19.7) | −8.25 (−11.35; −5.15) <0.001 | 12.6 (6.0) | −2.22 (−3.18; −1.25) <0.001 | 53.7 (20.4) | 9.84 (6.54; 13.13) <0.001 | 57.6 (32.3) | 17.55 (11.47; 23.62) <0.001 |
Antifibrotic therapy | |||||||||
No | 372 (50.5%) | 59.7 (20.9) | (ref) | 14.0 (5.9) | (ref) | 46.8 (21.7) | (ref) | 46.2 (32.0) | (ref) |
Yes | 365 (49.5%) | 60.3 (18.4) | 0.63 (−2.48; 3.74) 0.691 | 13.8 (6.2) | −0.19 (−1.17; 0.78) 0.698 | 49.9 (19.4) | 3.05 (−0.29; 6.38) 0.074 | 49.4 (30.3) | 3.13 (−3.04; 9.31) 0.319 |
Long-term oxygen therapy | |||||||||
No | 503 (68.3%) | 65.8 (17.9) | (ref) | 15.2 (5.7) | (ref) | 42.0 (19.2) | (ref) | 36.4 (27.3) | (ref) |
Yes | 234 (31.8%) | 47.8 (17.9) | −17.93 (−20.96; −14.90) <0.001 | 11.1 (5.7) | −4.15 (−5.14; −3.17) <0.001 | 61.2 (17.3) | 19.18 (16.08; 22.28) <0.001 | 71.2 (24.9) | 34.83 (29.40; 40.25) <0.001 |
Other non-pharmacological therapyb | |||||||||
No | 721 (97.8%) | 60.3 (19.7) | (ref) | 14.0 (6.0) | (ref) | 48.1 (20.6) | (ref) | 47.5 (31.1) | (ref) |
Yes | 16 (2.2%) | 49.4 (19.1) | −10.86 (−20.35; −1.37) 0.025 | 10.3 (6.4) | −3.71 (−6.87; −0.54) 0.022 | 56.3 (23.0) | 8.24 (−3.55; 20.04) 0.17 | 66.4 (30.5) | 18.98 (−2.30; 40.25) 0.08 |
Pulmonary rehabilitation | |||||||||
Unknown | 219 (30.3%) | 57.7 (20.5) | −4.04 (−7.57; −0.50) 0.025 | 13.5 (6.3) | −0.69 (−1.80; 0.42) 0.222 | 50.8 (21.2) | 4.56 (0.78; 8.34) 0.018 | 52.8 (34.0) | 8.32 (1.01; 15.63) 0.026 |
No | 464 (64.3%) | 61.8 (19.2) | (ref) | 14.2 (6.0) | (ref) | 46.3 (20.4) | (ref) | 44.5 (29.7) | (ref) |
Yes | 39 (5.4%) | 51.5 (19.4) | −10.24 (−17.14; −3.33) 0.004 | 11.9 (5.3) | −2.25 (−4.20; −0.31) 0.023 | 60.7 (17.1) | 14.42 (8.20; 20.64) <0.001 | 67.2 (27.6) | 22.63 (10.20; 35.06) <0.001 |
Reflux therapy | |||||||||
No | 510 (69.2%) | 61.8 (19.7) | (ref) | 14.3 (6.0) | (ref) | 46.4 (20.3) | (ref) | 44.5 (30.2) | (ref) |
Yes | 227 (30.8%) | 56.1 (19.3) | −5.67 (−8.99; −2.34) 0.001 | 12.8 (5.9) | −1.53 (−2.57; −0.48) 0.004 | 52.7 (20.8) | 6.31 (2.67; 9.94) 0.001 | 54.7 (32.1) | 10.13 (3.45; 16.80) 0.003 |