Fig. 9
From: Forced expiration measurements in mouse models of obstructive and restrictive lung diseases
Provocative methacholine concentrations in mice. Mean FEV0.1 concentration-response curves to MCh are shown for HDM-asthma and naive controls, with indication of corresponding provocative concentration inducing a 20% (PC20) (a), 30% (PC30) (c), or 40% (PC40) (e) decrease in baseline FEV0.1. PC20, PC30, and PC40, calculated from the concentration-response data for each individual mouse and group means are shown in b, d, and f, respectively. * p < 0.05, *** p < 0.001 compared to naive control group. n = 7 –8 per group