Table 5 Demographic comparison of retrospective studies on beta-blocker use in COPD
Study | Bhatt et al. [20] | Rutten et al. [11] | Short et al. [21] | Van Gestel et al. [16] | Current Study | |
|---|---|---|---|---|---|---|
MACRO4 | STATCOPE3 | |||||
N (on Beta blockers) | 474 | 665 | 796 | 462 | 110 | 63 |
Age | 66.8 | 64.7 | 69.8 | 69 | 67.3 | 63.4 |
% Men | 60.1% | 49.8% | 42.7% | 82.0% | 67.6% | 55.6% |
Mean Pack years | 56.8 | n/a | 44.3 | n/a | 59.4 | 49.1 |
% Current Smoker | n/a | 34.6% | n/a | 35.0% | 21.6% | 34.9% |
FEV1 (L) | 1.5 | n/a | n/a | n/a | 1.31 | 1.3 |
FEV1 mean % predicted | 53.2% | n/a | 65% | n/a | 46.8% | 45.8% |
% GOLD 3/4 | 38.4% | n/a | n/a | n/a | 55.8% | 61.9% |
%Chronic bronchitis | n/a | n/a | n/a | n/a | 50.5% | 52.5% |
% CAD or revasc | 44.7% | 38.3% (IHD) | 70% (CV dz) | 25% | 50% | 3% |
% Diabetes | 24.1% | 24.1% | 21% | 17% | 23% | 5% |
% Hypertension | 84.4% | 66.8% | n/a | 49% | 82% | 84% |
% History of MI | n/a | 9.6% | n/a | 33% | 38% | 5% |