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Fig. 4 | Respiratory Research

Fig. 4

From: Human adipose-derived mesenchymal stem cells alleviate obliterative bronchiolitis in a murine model via IDO

Fig. 4

Effect of IDO inhibitor 1-MT and ASCs on tracheal allografts. C57BL/6 mice were transplanted heterotopically with tracheas from C57BL/6 (isograft) or BALB/c (allograft). In the allograft group, PBS (0.2 ml, IV), ASCs (1 × 106 cells/0.2 ml, IV), or ASCs + 1-MT (10 mg, oral gavage) were administered to recipient mice on days 0, 1, 3, 5, 8, 12, 15, 20 and 25 post-transplant. Tracheal grafts were harvested on days 3, 7, 14, and 28 post-transplant. Histopathologic sections of grafts were stained with H&E. All images were 100 X magnification

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