Outcome

1min STS test (n = 371)

Handgrip strength test (n = 409)


Mortality

Hazard ratio (95% CI)
 
Hazard ratio (95% CI)

Per 1 more rep

0.93 (0.89 to 0.97)

Per 1 more kg

0.97 (0.94 to 1.00)

Per 3 more reps

0.81 (0.65 to 0.86)

Per 5 more kg

0.86 (0.73 to 1.01)

Exacerbations

Incidence rate ratio (95% CI)
 
Incidence rate ratio (95% CI)

Per 1 more rep

1.00 (0.99 to 1.02)

Per 1 more kg

1.00 (0.98 to 1.02)

Per 3 more reps

1.01 (0.93 to 1.09)

Per 5 more kg

1.00 (0.92 to 1.08)

HRQoL

Effect (95% CI)
 
Effect (95% CI)

CRQ dyspnoea

Per 1 more rep

0.05 (0.03 to 0.06)

Per 1 more kg

0.02 (−0.00 to 0.03)

Per 3 more reps

0.15 (0.16 to 0.32)

Per 5 more kg

0.08 (−0.00 to 0.15)

CRQ fatigue

Per 1 more rep

0.03 (0.02 to 0.05)

Per 1 more kg

0.02 (0.01 to 0.04)

Per 3 more reps

0.10 (0.06 to 0.14)

Per 5 more kg

0.12 (0.06 to 0.18)

CRQ emotional function

Per 1 more rep

0.01 (0.00 to 0.03)

Per 1 more kg

0.01 (−0.00 to 0.02)

Per 3 more reps

0.04 (0.00 to 0.08)

Per 5 more kg

0.03 (−0.02 to 0.09)

CRQ mastery

Per 1 more rep

0.02 (0.01 to 0.03)

Per 1 more kg

0.01 (−0.00 to 0.02)

Per 3 more reps

0.05 (0.02 to 0.09)

Per 5 more kg

0.04 (−0.01 to 0.10)

 All models were adjusted for age, sex, FEV_{1} L, CRQ dyspnoea and LABA/ICS, except the model with CRQ dyspnoea as the outcome, which was not adjusted for dyspnoea. The models for exacerbations were additionally adjusted for the number of exacerbations in the year before baseline. CRQ score is from 0–7, 0 = maximal impairment, 7 = no impairment.

Abbreviations: 1min STS test 1min sittostand test, rep repetition, HRQoL healthrelated quality of life, CRQ Chronic Respiratory Questionnaire, CI confidence interval