Table 1 Baseline characteristics of the participants
Characteristics | All participants (n = 854) |
|---|---|
Age (mean, SD) | 68.3 (7.6) |
Male (N, %) | 776 (90.9) |
Cohorts registration (N, %) | |
SNUH | 101 (11.8) |
CODA | 110 (12.9) |
KOCOSS | 325 (38.1) |
KOLD | 318 (37.2) |
BMI (mean, SD) | 23.0 (3.4) |
Weight (mean, SD) | 61.7 (10.7) |
Height (mean, SD) | 163.6 (7.4) |
Smoking habits | |
None smoker | 81/851 (9.5) |
Ex-smoker | 538/851 (63.2) |
Current smoker | 232/851 (27.3) |
Pack-year (mean, SD) | 43.3 (28.7) |
Comorbidities (N, %) | |
Diabetes mellitus | 111/825 (13.5) |
Heart disease | 67/841 (8.0) |
Cancer | 24/519 (4.6) |
Symptom scores | |
CAT (mean, SD) | 15.4 (7.9) |
CAT ≥10 (N, %) | 455/614 (74.1) |
SGRQ (mean, SD) | 33.1 (17.3) |
SGRQ ≥25 (N, %) | 258/418 (61.7) |
mMRC (mean, SD) | 1.61 (1.01) |
mMRC ≥2 (N, %) | 403/834 (48.3) |
Severe acute exacerbation within 1-year before enrollment (N, %) | 93 (10.9) |
Pulmonary function test, mean(SD) | |
Initial FVC post (L)/(%) | 3.18 (0.82)/87.6 (18.6) |
Initial FEV1 post (L)/(%) | 1.56 (0.55)/60.9 (19.7) |
Initial FEV1 ≥ 50% (N, %) | 586 (68.6) |
Initial FEV1/FVC ratio post, mean(SD) | 49.2 (11.7) |
BDR criteria, N (%) | |
BDR >12% and 200 ml (FEV1) (GOLD) | 167 (19.6) |
BDR ≥12% and 200 ml (FEV1 or FVC) (ATS) | 255 (29.9) |
BDR ≥15% (FEV1) (ACCP) | 187 (21.9) |
BDR >8% (FEV1) | 383 (44.9) |
BDR ≥15% and 400 ml (FEV1) (Spanish ACOS) | 30 (3.5) |
BDR >12% and 400 ml (FEV1) (ACOS GINA) | 30 (3.5) |
Post FEV1% - pre FEV1 % ≥ 10% (ERS) | 124 (14.5) |