Blood and sputum eosinophils in COPD; relationship with bacterial load

Respiratory Research

Table 2 PPM load and sputum inflammatory cell counts in patients with and without eosinophilic inflammation

Sputum	≥3% (n = 18)	<3% (n = 76)	p value
PPM load (copies/ml)	0.0 [0.0–8.2 × 10⁷]	2.7 × 10⁵ [0–4.9 × 10⁸]	0.046
Neutrophil %	68.4 [7.0–89.8]	80.1 [1.0–99.3]	0.04
Macrophage%	17.4 [2.9–85.5]	15.3 [0.5–88.5]	0.27
Eosinophil %	5.9 [3.0–13.2]	0.5 [0.0–3.0]	<0.0001
Lymphocyte %	0.0 [0.0–3.0]	0.0 [0.0–6.0]	0.16
Epithelial %	4.0 [0.5–33.0]	2.5 [0.0–89.3]	0.26
Total cell count x10⁶/g	4.0 [0.2–9.9]	3.4 [0.2–84.6]	0.62
Neutrophil cell count x10⁶/g	2.1 [0.0–7.7]	2.5 (0.0–82.4]	0.38
Macrophage cell count x10⁶/g	0.7 [0.0–2.3]	0.5 [0.1–4.2]	0.68
Eosinophil cell count x10⁶/g	0.2 [0.0–0.5]	0.0 [0.0–0.4]	<0.0001
Lymphocyte cell count x10⁶/g	0.0 [0.0–0.1]	0.0 [0.0–0.3]	0.13
Epithelial cell count x10⁶/g	0.1 [0.0–0.6]	0.10 [0.00–2.3]	0.46

ISSN: 1465-993X