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Table 1 Baseline demographics of the patients enrolled onto the study

From: Blood and sputum eosinophils in COPD; relationship with bacterial load

Characteristics

n

 

Age, yrs

168

69.8 (8.1)

Gender, (% Male)

168

74

Current Smoker, (%)

168

32

Inhaled steroid use (%)

168

86

Inhaled steroid dose (μg) (BDP equivalent)

168

1000 [200–2000]

LABA use (%)

168

88

LAMA use (%)

168

78

Pack Years

168

47.0 [10.0–220.0]

BMI (kg/m2)

168

26.2 [18.0–45.0]

FFMI (kg/m2)

159

17.8 (3.5)

Chronic Bronchitis (%)

164

73

Exacerbation rate (prior study entry)

168

1.0 [0.0–15.0]

SGRQ total

162

47.8 (18.4)

mMRC score

145

2.0 [1.0–4.0]

CAT score

165

18.7 (7.1)

6MWD

132

380.9 (109.4)

KCO, %

119

75.4 (27.0)

Pre FEV1 (L)

104

1.5 (0.6

Pre FEV1%

104

55.7 (19.9)

Pre FVC (L)

104

3.0 (0.9)

Pre FEV1/FVC

104

0.5 (0.1)

Post FEV1 (L)

168

1.5 (0.6)

Post FEV1%

168

56.8 (18.9)

Post FVC (L)

168

3.0 (0.9)

Post FEV1/FVC

168

0.5 (0.1)

Reversibility %

105

7.2 [−13.0–32.5]

Reversibility ml

105

100 [−180–420]

Sputum Total Cell Count x106/g

90

3.7 [0.2–84.6]

Sputum Neutrophil %

94

76.0 [1.0–99.3]

Sputum Eosinophil %

94

0.8 [0.0–13.2]

Sputum Neutrophil cell count x106/g

90

2.5 [0.0–82.4]

Sputum Eosinophil cell count x106/g

90

0.03 [0.0–0.5]

PPM positive (≥1 × 104 copies/ml), %

168

52

  1. Summaries are presented as mean (SD), median [Range] and percentages as appropriate
  2. Definitions of abbreviations: BDP Beclometasone dipropionate equivalent, LABA Long Acting Beta Agonist, LAMA Long Acting muscarinic antagonist, BMI Body Mass Index, FFMI, Fat Free Mass Index; SGRQ St George’s Respiratory Questionnaire, mMRC modified Medical Research Council, CAT COPD Assessment Test, 6MWD 6 min walk test, FEV 1 Forced Expired Volume in first second, FVC Forced vital capacity, PPM Potentially pathogenic microorganism, Pre Pre bronchodilator, Post Post bronchodilator