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Table 1 Characteristics of the total Lund cohort

From: Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease

 

Controls

(n = 40)

COPD

(n = 82)

Sex (male/female)

19/21

46/36

Smoking status (current/former)

7/32a

24/58

Age (years)

68 (66–70)

67 (62–69)

Pack-years

26 (21–36)a

37 (27–48)**

BMI (kg/m2)

27 (23–28)

26 (23–29)

FEV1 (%predicted)

94 (90–103)

60 (49–72)***

FEV1/FVC

0.77 (0.73–0.79)

0.53 (0.44–0.62)***

RV (%predicted)

117 (102–128)

144 (116–165)***

TLC (%predicted)

106 (99–111)

113 (102–122)*

RV/TLC

0.41 (0.38–0.46)

0.47 (0.42–0.54)***

VA (%predicted)

90 (86–99)

86 (79–94)*

DLCO (%predicted)

76 (69–89)

58 (48–68)***

DLCO/VA (%predicted)

88 (78–96)

69 (57–82)***

  1. Pulmonary function data is post inhalation of β2 agonist (400 μg salbutamol). Data presented as median (interquartile range). Pack years is defined as the equivalent of smoking 1 pack per day for a year
  2. BMI body mass index, RV residual volume, TLC total lung capacity, VA alveolar volume, DL CO diffusion lung capacity
  3. * p < 0.05; ** p < 0.01 and *** p < 0.001
  4. amissing data from 1 patient. * depicts significantly different from controls
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Respiratory Research

ISSN: 1465-993X

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