Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

Table 4 Cell type enrichement for the three FEV₁ associated modules

Reference dataset	Cell type	Module	rho*	Permutation best rho
Allantaz et al. (Discovery)	Neutrophil	Green	0.747	0.216
Allantaz et al. (Validation)	Neutrophil	Green	0.715	0.193
Naranbhai et al.	Neutrophil	Green	0.656	0.186
Allantaz et al. (Discovery)	Neutrophils	Yellow	0.773	0.147
Allantaz et al. (Validation)	Neutrophils	Yellow	0.729	0.145
Naranbhai et al.	Neutrophils	Yellow	0.697	0.143
Allantaz et al. (Discovery)	CD4+ T cells	Brown	0.618	0.121
Allantaz et al. (Discovery)	CD8+ T cells	Brown	0.589	0.127
Allantaz et al. (Validation)	CD8+ T cells	Brown	0.571	0.118
Allantaz et al. (Discovery)	CD56+ NK cells	Brown	0.568	0.122
Allantaz et al. (Validation)	CD4+ T cells	Brown	0.567	0.109
Allantaz et al. (Validation)	NK cells	Brown	0.536	0.142
Allantaz et al. (Discovery)	CD14+ monocytes	Brown	0.531	0.129

*donates P < 1×10⁻³⁰⁸ for all the reported Spearman’s rho values. Permutation best rho: the highest rho value obtained during permutation

ISSN: 1465-993X