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Table 1 Subjects demographics

From: Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

Variable

 

Discovery

Replication

P-value*

N

 

238 COPD

323 COPD

58 controls

 

Age

 

64.2 ± 6.2

63.9 ± 6.1

59.6 ± 6.5

<0.001

Male

 

64.3%

67.8%

62.1%

0.556

BMI

 

28.1 ± 6

26.5 ± 5.8

28.6 ± 4.3

0.001

Smoker

    

<0.001

Former

96.6%

54.5%

53.4%

 

Current

3.4%

45.5%

0%

 

Never

0%

0%

46.6%

 

Pack years

 

46 ± 26.9

48.2 ± 26.4

26.9 ± 14.1

<0.001

FEV1% predicted

 

49.5 ± 16.2

49.7 ± 15.9

109.7 ± 15.8

<0.001

FEV1/FVC

 

0.46 ± 0.13

0.45 ± 0.11

0.79 ± 0.06

<0.001

GOLD

    

--

2

43.7%

39.6%

--

 

3

44.1%

49.2%

--

 

4

12.2%

11.1%

--

 

Exacerbations in prior year

 

1.6 ± 1.8

0.4 ± 0.5

--

<0.001

  1. *P-value is from F test for continuous variables and chi-square test for categorical variables