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Table 1 Subjects demographics

From: Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

Variable   Discovery Replication P-value*
N   238 COPD 323 COPD 58 controls  
Age   64.2 ± 6.2 63.9 ± 6.1 59.6 ± 6.5 <0.001
Male   64.3% 67.8% 62.1% 0.556
BMI   28.1 ± 6 26.5 ± 5.8 28.6 ± 4.3 0.001
Smoker      <0.001
Former 96.6% 54.5% 53.4%  
Current 3.4% 45.5% 0%  
Never 0% 0% 46.6%  
Pack years   46 ± 26.9 48.2 ± 26.4 26.9 ± 14.1 <0.001
FEV1% predicted   49.5 ± 16.2 49.7 ± 15.9 109.7 ± 15.8 <0.001
FEV1/FVC   0.46 ± 0.13 0.45 ± 0.11 0.79 ± 0.06 <0.001
GOLD      --
2 43.7% 39.6% --  
3 44.1% 49.2% --  
4 12.2% 11.1% --  
Exacerbations in prior year   1.6 ± 1.8 0.4 ± 0.5 -- <0.001
  1. *P-value is from F test for continuous variables and chi-square test for categorical variables