Fig. 6From: Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in ratsEffect of FK866 on lung pathology. As shown by a representative micrograph of lung tissue (400× magnification) (a), neutrophil infiltration and septal edema were increased in the ischemia-reperfusion (IR) group. FK866 treatment significantly attenuated these histopathological changes, the numbers of neutrophils per high power field (400× magnification) (b), and the lung injury scores (c). Data are expressed as mean ± SD (n = 6 per group). ***p < 0.001, compared with the control group; +++ p < 0.001, compared with the IR groupBack to article page