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Fig. 5 | Respiratory Research

Fig. 5

From: Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats

Fig. 5

Effect of FK866 on protein carbonyl contents, MDA levels, and MPO-positive cells in lung tissue. MPO-positive cells (a), carbonyl contents (b), and MDA levels (c) in lung tissue significantly increased in the ischemia-reperfusion (IR) group. FK866 treatment significantly attenuated these increases. a Immunohistochemistry for MPO in the lung (indicated with arrowhead) (200× magnification). Data are expressed as mean ± SD (n = 6 per group). ***p < 0.001, compared with the control group; ++ p < 0.01, +++ p < 0.001, compared with the IR group

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