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Fig. 3 | Respiratory Research

Fig. 3

From: Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats

Fig. 3

Effect of FK866 on NAMPT protein expression in lung tissue. a Immunohistochemistry for NAMPT in the lung (indicated with arrowhead) (200× magnification). b Western blot and densitometry analysis of NAMPT protein in the lung tissue. β-actin served as loading control for cytoplasmic proteins. Representative blots are shown. Ischemia-reperfusion (IR) significantly increased positive staining and protein expression of NAMPT in the lung tissue. FK866 significantly decreased the degree of NAMPT positive staining and protein expression. Data are expressed as mean ± SD (n = 6 per group). **p < 0.01, compared with the control group; + p < 0.05, compared with the IR group

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