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Fig. 4 | Respiratory Research

Fig. 4

From: Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

Fig. 4

Lung histological analysis at the end of a 5-h low tidal volume mechanical ventilation (MV) following either a lipopolysaccharide (LPS) or vehicle (saline) aspiration in wild type (WT) and interleukin-6 knock-out (IL-6KO) mice receiving either recombinant human interleukin-6 (rHuIL-6) or vehicle (saline). a Global lung injury score. b Lung edema score. c Alveolitis score. d Lung leukocyte infiltration score. e Lung congestion score. The symbol * denotes Benjamini-Hochberg corrected p value < 0.05 of Mann-Whitney pairwise comparisons (following Kruskal Wallis test). Data are presented as box and whiskers plots. N = 6 to 8 animals per group

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