Fig. 1

Bronchoalveolar lavage data and lung histological analysis in wild-type adult mice subjected to lipopolysaccharide (LPS) aspiration, followed by 5-h low tidal volume mechanical ventilation (MV) and their control groups (four groups: control, MV, LPS and LPS + MV; five comparisons: control vs. MV, control vs. LPS, control vs. LPS + MV, MV vs. LPS + MV, LPS vs. LPS + MV). The lung injury score, total cell count, and total protein, IL-6, TNFα and MIP-2 concentrations in BAL fluid were assessed. The symbols §, ‡ and † denote Benjamini-Hochberg corrected p values <0.05 of Mann-Whitney pairwise comparisons (after Kruskal Wallis test) between the group so marked and the group that received MV alone, LPS alone and the combination LPS + MV, respectively. Data are presented as box and whiskers plots. N = 8–10 animals per group