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Table 1 Baseline characteristics of COPD patients and smokers without COPD included in the study

From: Telomere shortening and accelerated aging in COPD: findings from the BODE cohort

Variable COPD cases
(N = 121)
Smokers
(N = 121)
p-value
Sex (male%) 66 62 N.S.
Age (years)a 57 ± 8 57 ± 8 N.S.
BMI (Kg/m2)a 27 ± 5 28 ± 4 N.S.
Smoking habitc
(pack-yrs)ac
60 ± 25 44 ± 22 <0.0001
Active smoking (%) 50 64 0.027
T/S ratioa 0.68 ± 0.25 0.88 ± 0.52 <0.0001
FEV1 (L)a 1.66 ± 0.7 2.9 ± 0.7 <0.0001
FEV1 (% pred)a 59 ± 21 101 ± 14 <0.0001
FVC (% pred)a 89 ± 22 108 ± 15 <0.0001
FEV1 / FVC (%)a 53 ± 12 76 ± 5 <0.0001
PaO2 (mmHg)a 72.3 ± 14.3 78.7 ± 10 <0.001
KCO (%) 79.6 ± 25.1 97.3 ± 21.3 0.001
IC/TLC (%) 36 ± 9 45 ± 8 <0.001
6MWD (m)a 523 ± 89 551 ± 76 0.03
mMRC dyspneab 1 (0–2) 0 (0–0) 0.006
BODE indexb 1 (0–3) 0 (0–1) <0.001
Charlson indexb 0 (0–1) 0 (0–0) N.S.
  1. Data are presented as amean ± SD and bmedian (25th-75thpc) and compared by Student’s t-test or Chi2 test. cNumber of packs of cigarettes smoked per day x number of years smoking. Percentage BMI body mass index, T/S ratio relative telomere length, FEV 1 forced expiratory volume in one second, FVC forced vital capacity, % pred per cent predicted. PaO 2 partial oxygen tension, K CO diffusion capacity of carbon monoxide, IC/TLC inspiratory to total lung capacity ratio, 6MWD six-min walk distance test. N.S non-significant