Cell migration regulated by microtubule-associated processes. Microtubule dynamics is regulated by plus-end trafficking proteins (+TIPs),+TIP stabilizing protein (e.g. adenomatous polyposis coli, APC), and cytoplasmic linker associated proteins (CLAPs). Microtubules regulate cell migration through their roles in mechanics, trafficking and signaling. GEF, guanine nucleotide exchange factor; MAP4K4, mitogen-activated protein kinase kinase kinase kinase 4.