Table 2 Unadjusted healthcare utilization, costs and health-related quality of life
From: Costs and health-related quality of life in Alpha-1-Antitrypsin Deficient COPD patients
Healthcare utilization | Subgroups | |||
A | B | B1 | B2 | |
(n = 2049) | (n = 131) | (n = 106) | (n = 25) | |
Outpatient services (3 months) | ||||
General practitioner | ||||
% User | 76 | 66 | 64 | 76 |
Number of visits | 1.9 (2.3) | 3.8 (4.8) | 4.1 (5.0) | 2.7 (3.7) |
Specialists | ||||
% User | 94 | 96 | 96 | 96 |
Number of visits | 4.4 (4.4) | 8.9 (7.4) | 9.6 (7.0) | 5.9 (8.5) |
Ambulant hospital visits | ||||
%User | 16 | 18 | 18 | 16 |
Number of visits | 0.3 (1.5) | 0.7 (3.0) | 0.8 (3.3) | 0.2 (0.4) |
Inpatient services (12 months) | ||||
% User | 39 | 24 | 24 | 24 |
Number of visits | 0.6 (1.1) | 0.3 (0.8) | 0.4 (0.9) | 0.3 (0.5) |
Duration of stay | 5.8 (14.1) | 2.3 (5.8) | 2.2 (5.7) | 2.7 (6.3) |
Rehabilitation (12 months) | ||||
Ambulant | ||||
% User | 2 | 4 | 3 | 8 |
Number of visits | 0.5 (4.2) | 0.6 (3.1) | 0.5 (2.8) | 1.16 (4.0) |
Stationary | ||||
% User | 14 | 21 | 22 | 16 |
Duration of stay | 3.3 (8.8) | 5.2 (10.9) | 5.4 (10.6) | 5.0 (12.3) |
Physiotherapist (12 months) | ||||
%User | 35 | 52 | 51 | 56 |
Number of visits | 7.1 (18.5) | 15.2 (23.6) | 15.2 (24.1) | 14.9 (22.1) |
Medication (7 days) | ||||
Number of prescribed medications (without AT) | 6.1 (3.2) | 4.7 (2.7) | 4.7 (2.6) | 4.4 (3.1) |
Direct costs (12 months) | ||||
Outpatient costs | 938 (834) | 2160 (1547) | 2423 (1559) | 1044 (857) |
Inpatient costs | 3441 (8302) | 1341 (3394) | 1285 (3337) | 1579 (3687) |
Rehabilitation | 433 (1086) | 674 (1327) | 675 (1293) | 666 (1487) |
Physiotherapist | 118 (307) | 252 (393) | 253 (400) | 247 (368) |
Medication costs | 2533 (3327) | 1961 (1076) | 2056 (1080) | 1558 (976) |
Medication costs including AT | 2533 (3327) | 60427 (28718) | 74311 (1080) | 1558 (976) |
Total direct costs | 7446 (9836) | 6374 (4535) | 6675 (4202) | 5096 (5655) |
Total direct costs incl. AT | 7446 (9836) | 64840 (29467) | 78930 (4202) | 5096 (5655) |
Indirect costs (participants < 65 years) | Subgroups | |||
A | B | B1 | B2 | |
(n = 897) | (n = 82) | (n = 69) | (n = 13) | |
Work absenteeism (12 months) | ||||
% retired | 47 | 35 | 37 | 23 |
% employed | 38 | 55 | 54 | 62 |
% thereof with sick days (12 months) | 73 | 67 | 59 | 100 |
Number of sick days | 30.8 (50.9) | 24.8 (46.7) | 24.2 (50.1) | 27.6 (28.0) |
Indirect costs (12 months) | ||||
Costs due to sick days (HC) | 5452 (9015) | 4395 (8278) | 4287 (8882) | 4895 (4965) |
Costs due to sick days (FC) | 2541 (2585) | 2161 (2392) | 1935 (2374) | 3208 (2338) |
Premature retirement (HC) | 17508 (18543) | 13129 (17859) | 13989 (18123) | 8568 (16280) |
Total indirect costs (HC) | 19514 (17615) | 15541 (17231) | 16288 (17595) | 11580 (15155) |
Total indirect costs (FC) | 935 (1989) | 1186 (2069) | 1038 (1982) | 1974 (2413) |
Health-related Quality of Life | Subgroups | |||
A | B | B1 | B2 | |
(n = 2049) | (n = 131) | (n = 106) | (n = 25) | |
SGRQ | 44.0 (20.0) | 44.8 (17.2) | 46.6 (16.4) | 37.5 (20.2) |
CAT | 18.3 (7.4) | 18.6 (6.7) | 18.9 (6.6) | 17.2 (7.3) |
EQ-5D-3 L utility | 81.5 (20.7) | 83.2 (19.1) | 83.0 (19.1) | 83.9 (19.4) |
EQ-5D VAS | 56.2 (19.4) | 56.4 (19.0) | 54.4 (18.8) | 63.6 (18.75) |