Table 4 Outcome in the study completers after 6 weeks of NIV

Change in CO, % of baseline

LIHI

−7.8 ± 14.9

3.2 ± 19.2

−8.5% (−27 to 10%)

0.33

HILI

17.7 ± 34.6

−10.3 ± 24.8

CO, L/min

LIHI

5.8 ± 1.1

5.3 ± 1.1

5.9 ± 1.2

−0.38 (−1.31 to 0.56)

0.39

HILI

5.1 ± 0.7

5.9 ± 1.1

4.5 ± 1.1

NTproBNP,pg/ml^##

LIHI

177 (117–317)

113 (63–197)

158 (67–208)

37 (−26 to 101)

0.22

HILI

215 (61–469)

199 (91–430)

158 (88–620)

PaCO₂, day, kPa

LIHI

6.7 ± 0.7

6.3 ± 0.7

6.1 ± 0.8*

−2.8 (−6.6 to 1.0)

0.13

HILI

7.0 ± 1.1

6.6 ± 0.7

6.0 ± 0.7*

FEV₁, L

LIHI

0.72 ± 0.14

0.79 ± 0.20*

0.75 ± 0.21*

−0.00 (−0.11 to 0.10)

0.93

HILI

0.95 ± 0.55

1.10 ± 0.63*

1.13 ± 0.63*

SRI-SS

LIHI

43.3 ± 20.2

52.2 ± 19.7*

49.8 ± 20.8*

−2.9 (−8.0 to 2.0)

0.22

HILI

45.2 ± 13.6

55.7 ± 8.4*

52.6 ± 9.9*