Impact of High-Intensity-NIV on the heart in stable COPD: a randomised cross-over pilot study

Respiratory Research

Table 1 Baseline characteristics of all patients

ID	Age yrs	Sex	BMI kg/m²	PaCO₂ day, kPa	PaO₂ day, kPa	HCO₃, day, mmol/L	PaCO₂ night, kPa	Δ PtCO₂ night, kPa	LTOT l/min	FEV₁ %pred	FEV₁/FVC, %
1	57	M	34.7	5.8	8.8	27.0	7.6	2.5	-	23	34
2	74	F	28.0	6.3	9.3	28.6	7.0	2.8	2.0	39	52
3	53	M	21.4	6.1	7.7	28.3	6.5	1.3	-	28	38
4	70	F	27.2	6.4	8.4	27.2	6.8	5.3	4.0	35	68
5	67	M	35.9	7.1	9.3	36.0	7.3	2.2	-	50	66
6	82	M	21.5	8.6	5.9	31.9	10.6	0.8	2.0	30	63
7	78	F	31.6	7.6	7.8	30.6	9.6	1.5	2.5	29	51
8	74	F	22.5	7.8	10.9	30.6	8.0	2.5	3.0	36	61
9	68	M	19.4	7.3	8.8	28.6	6.9	2.7	4.0	36	40
10	63	F	22.8	7.4	8.6	29.3	8.2	1.3	3.0	18	39
11	71	F	25.1	5.9	9.6	27.0	7.4	2.6	1.0	35	66
12	63	F	27.8	8.1	8.7	28.4	8.8	4.6	3.0	37	61
13	60	F	18.3	9.4	7.1	38.5	8.8	1.9	3.0	11	38
14	77	F	18.7	6.4	10.2	28.0	7.5	1.0	2.0	41	49
Mean	68.7		25.2	6.8	8.9	29.3	7.0	2.3		34	53
SD	8.5		5.8	0.9	1.3	2.7	2.5	1.2		9	13

ID 7, 12 and 13 (italic) were excluded from analysis as they dropped out of the study. The mean and standard deviation (SD) of the 11 patients included in the full data set analysis are shown
BMI body mass index, PaO ₂ partial arterial oxygen pressure in kilopascal (kPa), PaCO ₂ partial arterial carbon dioxide pressure in kPa, HCO ₃ ⁻ bicarbonate, Δ PtCO ₂ increase in transcutaneous carbon dioxide pressure measured continuously at the ear lobe during the night; all blood gasses measured without NIV and with the regular amount of oxygen prescribed
FEV ₁ forced expiratory volume in 1 s, FVC forced vital capacity

ISSN: 1465-993X