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Fig. 4 | Respiratory Research

Fig. 4

From: ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling

Fig. 4

Effects of paclitaxel, doxorubicin and gemcitabine treatment. Relative mRNA expression of ABCB1, ABCG2, ABCC1 and ABCC2 were studied following treatment of a) 3D co-culture aggregates of adenocarcinoma cell line A549 and NHLF; and b) 3D co-culture aggregates of squamous cell carcinoma cell line H520 and NHLF; with 100 nM paclitaxel, 100 nM doxorubicin, 100 nM gemcitabine for 48 h. mRNA expression was normalized to beta-actin. Data are presented as mean ± SEM, n = 3

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Respiratory Research

ISSN: 1465-993X

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