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Fig. 1 | Respiratory Research

Fig. 1

From: ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling

Fig. 1

Drug transporter and Wnt microenvironment analysis of primary human AC and SCC samples. Relative mRNA expression of a) ABCB1 and ABCG2 drug transporters and b) non-canonical Wnt5a and canonical Wnt7b in primary human AC and SCC samples. mRNA expression is relative to normal, healthy lung tissue. n = 76 for AC, and n = 14 for SCC. Data are presented as mean ± SEM. Immunohistochemistry of primary AC and SCC of c) ABCB1 drug transporter protein staining (n = 5 each) and d) Wnt5a ligand protein staining (n = 5 each). Magnification is 20×, scale bar 100 μm

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