Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension

Table 2 Cardiac morphometry parameters in control and MCT-treated (at 2, 4, and 6 weeks) rats

Group	CON-2 W (n = 8)	MCT-2 W (n = 12)	CON-4 W (n = 8)	MCT-4 W (n = 10)	CON-6 W (n = 8)	MCT-6 W (n = 8)
RV/LV + IVS (g/g)	0.24 ± 0.02	0.27 ± 0.02^*	0.25 ± 0.02	0.48 ± 0.06^**※※	0.23 ± 0.03	0.62 ± 0.09 ^**※※△
RV/BW (g/kg)	0.48 ± 0.02	0.53 ± 0.02^*	0.49 ± 0.04	0.85 ± 0.06^**※※	0.45 ± 0.03	1.22 ± 0.07^**※※△

BW Body weight, LW Lung weight, RV Right ventricle, LV Left ventricle, IVS Interventricular septum, MCD Myocardium cell diameter
Data are presented as mean ± standard deviation. ^* P < 0.05 and ^** P < 0.01, versus age-matched rat; ^※ P < 0.05, ^※※ P < 0.01, versus MCT-2 W; ^△ P < 0.05, versus MCT-4 W

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