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Fig. 7 | Respiratory Research

Fig. 7

From: Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension

Fig. 7

HIF-1α/Bcl2/BNIP3/Beclin-1 signaling pathways are distinctly dysregulated in RV of MCT rat model. a Western blot analysis of HIF-1α, Bcl2, BNIP3 and Beclin-1 protein in RV protein extracts from control and MCT-treated rats for 2, 4, and 6 weeks. β-actin was used as a loading control. b-e Quantification of HIF-1α, Bcl2, BNIP3, and Beclin-1 protein band signal densities was performed using ImageJ software and plotted normalized to β-actin levels. Values are presented as mean ± standard deviation. * P < 0.05, ** P < 0.01

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Respiratory Research

ISSN: 1465-993X

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