Respiratory Research

Table 3 Association of Soluble CD14 Levels with FEV₁ & FEV₁/FVC: Stratified by COPD and Smoking Status

From: Interaction of CD14 haplotypes and soluble CD14 on pulmonary function in agricultural workers

FEV ₁ (% predicted)
	COPD, Ever Smoker		COPD, Never smoker		No COPD, Ever Smoker		No COPD, Never Smoker
sCD14	n	Mean ± SE	n	Mean ± SE	n	Mean ± SE	n	Mean ± SE
≤ Median	104	69.8 ± 1.7	7	91.2 ± 6.7	121	88.2 ± 1.6	57	89.1 ± 2.3
> Median	104	60.9 ± 1.7	12	78.0 ± 5.1	134	87.9 ± 1.5	37	90.6 ± 2.9
	p	0.0003	p	0.12	p	0.88	p	0.69
	^ap_adj	0.0008	^ap_adj	0.26	^ap_adj	0.91	^ap_adj	0.81
% FEV ₁ /FVC
sCD14	n	Mean ± SE	n	Mean ± SE	n	Mean ± SE	n	Mean ± SE
≤ Median	104	61.0 ± 0.74	7	67.0 ± 2.9	121	76.3 ± 0.7	57	77.6 ± 1.0
> Median	104	56.0 ± 0.74	12	62.9 ± 2.2	134	76.3 ± 0.7	37	77.0 ± 1.2
	p	<0.0001	p	0.26	p	0.93	p	0.73
	^ap_adj	0.0002	^ap_adj	0.53	^ap_adj	0.52	^ap_adj	0.86

Abbreviations and Definitions: sCD14, soluble CD14; FEV₁, forced expiratory volume in 1 s; % FEV₁/FVC, FEV₁/FVC x 100; FVC, forced vital capacity; COPD, FEV₁/FVC < 0.70; ever smokers, current and former smokers
^aMultivariable results (p_adj) are adjusted for age, body mass index, education, sex, race and years worked on a farm
P-values adjusted for multiple comparisons with Tukey’s method

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ISSN: 1465-993X

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