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Table 3 Unadjusted hazard ratios for death or transplant (A) and for death in those who did not undergo transplant (B) for measurements dichotomized at their medians

From: Densitometric and local histogram based analysis of computed tomography images in patients with idiopathic pulmonary fibrosis

Measurement

Hazard ratio for death or transplant

p

Hazard ratio for deatha

p

Quantitative Densitometric

 Mean Lung Density (High vs. Low)

3.27

0.006

5.05

0.015

 Skewness (Low vs. High)

2.92

0.012

3.56

0.039

 Kurtosis (Low vs. High)

4.49

0.001

4.37

0.013

 High Attenuating Area (High vs. Low)

3.17

0.007

7.69

0.009

Qualitative

 Fibrosis Score, fibrosis% (High vs. Low)

3.48

0.003

3.96

0.026

Quantitative Feature Based

 Quantitative Interstitial Score, interstitial% (High vs. Low)

2.30

0.065

3.51

0.065

 Percentage of Interstitial Disease Occupied by Honeycombing, Honeycombing% (High vs. Low)

3.28

0.014

2.86

0.094

Pulmonary Function Test

 FVC percent predicted (Low vs. High)

2.80

0.016

3.14

0.063

 DLCO percent predicted (Low vs. High)

3.78

0.012

3.38

0.100

  1. Abbreviations: diffusing capacity of carbon monoxide (DLCO), forced vital capacity (FVC). aIn the subgroup who did not undergo transplantation