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Table 1 Characteristics of the cohort

From: Densitometric and local histogram based analysis of computed tomography images in patients with idiopathic pulmonary fibrosis

Gender

Number

Percent

 Male

33

71.7

Race

Number

Percent

 White

38

82.6

 Black

2

4.35

 Asian

3

6.5

 Hispanic

3

6.5

Pulmonary Function

Mean (Standard Deviation)

Median, Interquartile Range

 FEV1 - L

2.03 (0.69)

2.02, [1.62, 2.45]

 FEV1 % predicted

64.76 (21.05)

64, [49, 82]

 FVC - L

2.40 (0.86)

2.36, [1.71, 2.91]

 FVC % predicted

60.17 (21.11)

58.5, [44.0, 73.0]

 DLCO – mL/min/mmHg

10.40 (3.99)

10.06, [7.75, 12.53]

 DLCO % predicted

39.61 (15.66)

37.0, [30.5, 48.5]

Quantitative CT Measures - Densitometric

Mean (Standard Deviation)

Median, Interquartile Range

 Mean Lung Density (HU)

-670.14 (86.24)

-680.46, [-733.31, -607.03]

 Skewness

1.35 (0.55)

1.40, [1.01, 1.79]

 Kurtosis

5.06 (2.32)

4.72, [3.18, 6.18]

 Percentage of Lung Occupied by High Attenuation Area, HAA%

17.21 (6.45)

15.41, [12.54, 23.13]

Qualitative CT Measures

Mean (Standard Deviation)

Median, Interquartile Range

 Fibrosis Score, fibrosis%

26.89 (15.80)

22.92, [14.17, 37.50]

Quantitative CT Measures - Feature Based

Mean (Standard Deviation)

Median, Interquartile Range

 Quantitative interstitial score, interstitial%

68.53 (18.39)

65.75, [57.53, 81.90]

 Percentage of Interstitial Disease Occupied by Honeycombing, Honeycombing%

26.36 (17.19)

21.65, [12.09, 38.04]

  1. Abbreviations: computed tomography (CT), diffusing capacity of carbon monoxide (DLCO), forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), Hounsfield units (HU), standard deviation (SD)