From: Associations between chronic comorbidity and exacerbation risk in primary care patients with COPD
 | Study populationa, (n = 14,603) | Patients with <2 exacerbations/year, (n = 13,709) | Patients with ≥2 exacerbations/year (n = 894) | p-valueb |
---|---|---|---|---|
Comorbidity category | ||||
 Cardiovascular | 8,516 (58 · 3) | 7,955 (58 · 0) | 561 (62 · 8) | 0 · 006 |
 Endocrine, metabolic and nutrition | 4,856 (33 · 3) | 4,568 (33 · 3) | 288 (25 · 5) | 0 · 496 |
 Musculoskeletal | 3,588 (24 · 6) | 3,337 (24 · 3) | 251 (28 · 1) | 0 · 012 |
 Eye and ear | 2,984 (20 · 4) | 2,762 (20 · 1) | 222 (24 · 8) | 0 · 001 |
 Digestive | 2,801 (19 · 2) | 2,597 (18 · 9) | 204 (22 · 8) | 0 · 004 |
 Urogenital (male and female) | 2,330 (16 · 0) | 2,146 (15 · 7) | 184 (20 · 6) | <0 · 001 |
 Psychiatric | 2,271 (15 · 6) | 2,092 (15 · 3) | 179 (20 · 0) | <0 · 001 |
 Non-pulmonary cancer | 2,203 (15 · 1) | 2,071 (15 · 1) | 132 (14 · 8) | 0 · 782 |
 Respiratory (excl · pulmonary cancer) | 1,998 (13 · 7) | 1,839 (13 · 4) | 159 (17 · 8) | <0 · 001 |
 Skin | 1,395 (9 · 6) | 1,314 (9 · 6) | 81 (9 · 1) | 0 · 605 |
 Neurological | 413 (2 · 8) | 389 (2 · 8) | 24 (2 · 7) | 0 · 789 |
 Pulmonary cancer | 317 (2 · 2) | 284 (2 · 1) | 33 (3 · 7) | 0 · 001 |
 Blood (forming organs) and lymphatics | 106 (0 · 7) | 97 (0 · 7) | 9 (1 · 0) | 0 · 307 |
 Infectious | 87 (0 · 6) | 80 (0 · 6) | 7 (0 · 8) | 0 · 453 |