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Table 3 Prevalence of ICPC-categorized comorbidity in the COPD study population, sorted from highest to lowest prevalence rate of frequent exacerbations

From: Associations between chronic comorbidity and exacerbation risk in primary care patients with COPD

 

Study populationa, (n = 14,603)

Patients with <2 exacerbations/year, (n = 13,709)

Patients with ≥2 exacerbations/year (n = 894)

p-valueb

Comorbidity category

 Cardiovascular

8,516 (58 · 3)

7,955 (58 · 0)

561 (62 · 8)

0 · 006

 Endocrine, metabolic and nutrition

4,856 (33 · 3)

4,568 (33 · 3)

288 (25 · 5)

0 · 496

 Musculoskeletal

3,588 (24 · 6)

3,337 (24 · 3)

251 (28 · 1)

0 · 012

 Eye and ear

2,984 (20 · 4)

2,762 (20 · 1)

222 (24 · 8)

0 · 001

 Digestive

2,801 (19 · 2)

2,597 (18 · 9)

204 (22 · 8)

0 · 004

 Urogenital (male and female)

2,330 (16 · 0)

2,146 (15 · 7)

184 (20 · 6)

<0 · 001

 Psychiatric

2,271 (15 · 6)

2,092 (15 · 3)

179 (20 · 0)

<0 · 001

 Non-pulmonary cancer

2,203 (15 · 1)

2,071 (15 · 1)

132 (14 · 8)

0 · 782

 Respiratory (excl · pulmonary cancer)

1,998 (13 · 7)

1,839 (13 · 4)

159 (17 · 8)

<0 · 001

 Skin

1,395 (9 · 6)

1,314 (9 · 6)

81 (9 · 1)

0 · 605

 Neurological

413 (2 · 8)

389 (2 · 8)

24 (2 · 7)

0 · 789

 Pulmonary cancer

317 (2 · 2)

284 (2 · 1)

33 (3 · 7)

0 · 001

 Blood (forming organs) and lymphatics

106 (0 · 7)

97 (0 · 7)

9 (1 · 0)

0 · 307

 Infectious

87 (0 · 6)

80 (0 · 6)

7 (0 · 8)

0 · 453

  1. ICPC International Classification of Primary Care
  2. aTotal COPD population, with patients who were lost to follow-up (n = 1,824) excluded
  3. b p-values displayed are calculated for the difference between the group <2 versus ≥2 exacerbations/year. We performed Chi-square tests for categorized variables. p-value <0 · 05 was considered statistically significant