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Table 4 Spearman’s correlations between biomarkers, clinical characteristics and blood cell counts in COPD patients regardless of subtype (n = 52)

From: Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD

 

FEV1 % of predicted

FVC % of predicted

6MWD

SF36 PCS

SF36 MCS

Eosinophils

C1M

  r

−0.252

−0.253

−0.271

−0.187

0.037

0.085

  p-value

0.08

0.07

0.05

0.19

0.80

0.55

EL-NE

  r

−0.060

−0.163

−0.274

−0.125

0.137

0.204

  p-value

0.65

0.25

0.05

0.09

0.33

0.15

C6M

  r

−0.091

−0.149

−0.311

−0.242

0.130

0.382

  p-value

0.53

0.30

0.028

0.09

0.37

0.006

Pro-C6

  r

0.239

0.281

−0.207

−0.361

−0.308

0.351

  p-value

0.09

0.046

0.14

0.009

0.028

0.012

  1. Correlations with a p-value ≤ 0.05 are highlighted in bold. FEV 1 Forced Expiratory Volume in 1 s, FVC Forced Vital Capacity, 6MWD 6 min Walking Distance, SF 36 PCS Physical Component Score of the SF 36 quality of life psychometric tool, SF-36 MCS Mental Component Score of the SF-36 quality of life psychometric tool. Higher score in the SF-36 reflects better health