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Table 4 Spearman’s correlations between biomarkers, clinical characteristics and blood cell counts in COPD patients regardless of subtype (n = 52)

From: Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD

  FEV1 % of predicted FVC % of predicted 6MWD SF36 PCS SF36 MCS Eosinophils
C1M
r −0.252 −0.253 −0.271 −0.187 0.037 0.085
p-value 0.08 0.07 0.05 0.19 0.80 0.55
EL-NE
r −0.060 −0.163 −0.274 −0.125 0.137 0.204
p-value 0.65 0.25 0.05 0.09 0.33 0.15
C6M
r −0.091 −0.149 −0.311 −0.242 0.130 0.382
p-value 0.53 0.30 0.028 0.09 0.37 0.006
Pro-C6
r 0.239 0.281 −0.207 −0.361 −0.308 0.351
p-value 0.09 0.046 0.14 0.009 0.028 0.012
  1. Correlations with a p-value ≤ 0.05 are highlighted in bold. FEV 1 Forced Expiratory Volume in 1 s, FVC Forced Vital Capacity, 6MWD 6 min Walking Distance, SF 36 PCS Physical Component Score of the SF 36 quality of life psychometric tool, SF-36 MCS Mental Component Score of the SF-36 quality of life psychometric tool. Higher score in the SF-36 reflects better health