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Table 2 Subtype analyses according to gender

From: Subtypes of asthma based on asthma control and severity: a latent class analysis

  Women Men
Mild Moderate Unknown severity Severe Mild Unknown severity Severe
  Controlled asthma Partly controlled asthma Uncontrolled asthma Uncontrolled asthma Controlled asthma Uncontrolled asthma Partly controlled asthma
Probability
(95% CI)
Probability
(95% CI)
Probability
(95% CI)
Probability
(95% CI)
Probability
(95% CI)
Probability
(95% CI)
Probability
(95% CI)
Class membership probabilities 0.41 (0.35–0.46) 0.24 (0.19–0.28) 0.26 (0.20–0.32) 0.09 (0.06–0.12) 0.31 (0.22–0.39) 0.53 (0.44–0.62) 0.17 (0.12–0.21)
Item Response probabilities
 Asthma controller medicationa
  Not at all 0.14 (0.11–0.18) 0.02 (0.00–0.03) 0.00 (0.00–0.01) 0.00 (0.00–0.00) 0.16 (0.09–0.22) 0.04 (0.01–0.06) 0.01 (0.00–0.03)
  Occasionally 0.22 (0.18–0.26) 0.12 (0.07–0.17) 0.13 (0.07–0.18) 0.06 (0.01–0.12) 0.20 (0.13–0.27) 0.14 (0.09–0.19) 0.09 (0.02–0.16)
  Daily 0.64 (0.59–0.69) 0.86 (0.81–0.91) 0.87 (0.82–0.93) 0.94 (0.88–0.99) 0.64 (0.56–0.73) 0.82 (0.76–0.87) 0.90 (0.83–0.97)
 Bronchodilator use
  Not at all 0.30 (0.25–0.34) 0.10 (0.05–0.14) 0.10 (0.05–0.14) 0.02 (0.00–0.05) 0.39 (0.30–0.49) 0.17 (0.12–0.23) 0.05 (0.00–0.11)
  Occasionally 0.67 (0.62–0.72) 0.75 (0.69–0.82) 0.59 (0.52–0.67) 0.57 (0.46–0.68) 0.61 (0.51–0.70) 0.54 (0.47–0.62) 0.45 (0.34–0.56)
  Daily 0.04 (0.01–0.06) 0.15 (0.09–0.21) 0.31 (0.23–0.38) 0.49 (0.38–0.60) 0.00 (0.00–0.01) 0.28 (0.21–0.35) 0.50 (0.39–0.61)
 Oral corticosteroid prescriptions
  0 prescriptions 0.97 (0.94–0.99) 0.41 (0.32–0.49) 0.78 (0.71–0.84) 0.11 (0.03–0.18) 1.00 (0.98–1.00) 0.90 (0.86–0.95) 0.28 (0.16–0.40)
  1 to 2 prescriptions 0.03 (0.00–0.05) 0.57 (0.49–0.66) 0.15 (0.09–0.21) 0.53 (0.41–0.65) 0.00 (0.00–0.02) 0.09 (0.04–0.13) 0.51 (0.39–0.63)
  ≥3 prescriptions 0.00 (0.00–0.00) 0.02 (0.00–0.05) 0.02 (0.00–0.03) 0.32 (0.21–0.43) 0.00 (0.00–0.00) 0.01 (0.00–0.02) 0.16 (0.08–0.24)
  Daily oral corticosteroid medication 0.01 (0.00–0.02) 0.00 (0.00–0.00) 0.06 (0.03–0.09) 0.04 (0.00–0.09) 0.00 (0.00–0.00) 0.00 (0.00–0.01) 0.05 (0.00–0.10)
 Antibiotics use
  0 prescription 0.98 (0.95–1.00) 0.42 (0.33–0.52) 0.97 (0.93–1.01) 0.08 (0.00–0.19) 0.99 (0.97–1.01) 0.95 (0.92–0.99) 0.37 (0.23–0.50)
  1 prescription 0.01 (0.00–0.03) 0.32 (0.25–0.40) 0.02 (0.00–0.05) 0.08 (0.00–0.16) 0.01 (0.00–0.03) 0.04 (0.01–0.06) 0.24 (0.14–0.33)
  2 prescriptions 0.01 (0.00–0.02) 0.17 (0.11–0.22) 0.01 (0.00–0.03) 0.20 (0.10–0.29) 0.00 (0.00–0.01) 0.01 (0.00–0.02) 0.19 (0.10–0.27)
  3 or more prescriptions 0.00 (0.00–0.01) 0.09 (0.04–0.14) 0.00 (0.00–0.03) 0.64 (0.49–0.78) 0.00 (0.00–0.00) 0.00 (0.00–0.01) 0.21 (0.12–0.30)
 St. George’s Scoreb
  0–7 points 0.48 (0.41–0.55) 0.15 (0.10–0.21) 0.03 (0.01–0.05) 0.00 (0.00–0.01) 0.59 (0.47–0.72) 0.14 (0.08–0.20) 0.07 (0.01–0.13)
  >7–15 points 0.32 (0.27–0.38) 0.31 (0.24–0.37) 0.15 (0.13–0.18) 0.09 (0.02–0.16) 0.21 (0.12–0.31) 0.26 (0.20–0.33) 0.04 (0.00–0.09)
  >15–27 points 0.15 (0.10–0.21) 0.35 (0.28–0.42) 0.36 (0.28–0.43) 0.17 (0.08–0.27) 0.19 (0.09–0.28) 0.27 (0.20–0.33) 0.28 (0.18–0.38)
  >27 points 0.04 (0.01–0.08) 0.19 (0.11–0.27) 0.49 (0.39–0.58) 0.74 (0.63–0.85) 0.00 (0.00–0.03) 0.33 (0.26–0.41) 0.62 (0.51–0.73)
 Health care facility use score
  0 point 0.97 (0.94–0.99) 0.36 (0.27–0.45) 0.88 (0.82–0.94) 0.13 (0.04–0.22) 0.96 (0.92–1.00) 0.92 (0.87–0.97) 0.37 (0.26–0.49)
  1 point 0.03 (0.01–0.06) 0.21 (0.15–0.27) 0.07 (0.03–0.11) 0.03 (0.00–0.07) 0.04 (0.01–0.08) 0.03 (0.00–0.06) 0.12 (0.05–0.19)
  2 to 3 points 0.00 (0.00–0.00) 0.38 (0.30–0.46) 0.05 (0.01–0.09) 0.48 (0.37–0.59) 0.00 (0.00–0.01) 0.05 (0.01–0.08) 0.34 (0.24–0.44)
  ≥4 points 0.00 (0.00–0.00) 0.05 (0.02–0.08) 0.00 (0.00–0.02) 0.36 (0.25–0.47) 0.00 (0.00–0.00) 0.00 (0.00–0.00) 0.17 (0.09–0.25)
  1. Probabilities over 50% or otherwise important for the characterization of each subtype are marked in bold
  2. aAsthma controller medication use includes both inhaled corticosteroids and combination medication of inhaled corticosteroid and long-acting beta-agonist
  3. bSt. George’s score range: 0-100
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