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Table 2 Subtype analyses according to gender

From: Subtypes of asthma based on asthma control and severity: a latent class analysis

 

Women

Men

Mild

Moderate

Unknown severity

Severe

Mild

Unknown severity

Severe

 

Controlled asthma

Partly controlled asthma

Uncontrolled asthma

Uncontrolled asthma

Controlled asthma

Uncontrolled asthma

Partly controlled asthma

Probability

(95% CI)

Probability

(95% CI)

Probability

(95% CI)

Probability

(95% CI)

Probability

(95% CI)

Probability

(95% CI)

Probability

(95% CI)

Class membership probabilities

0.41 (0.35–0.46)

0.24 (0.19–0.28)

0.26 (0.20–0.32)

0.09 (0.06–0.12)

0.31 (0.22–0.39)

0.53 (0.44–0.62)

0.17 (0.12–0.21)

Item Response probabilities

 Asthma controller medicationa

  Not at all

0.14 (0.11–0.18)

0.02 (0.00–0.03)

0.00 (0.00–0.01)

0.00 (0.00–0.00)

0.16 (0.09–0.22)

0.04 (0.01–0.06)

0.01 (0.00–0.03)

  Occasionally

0.22 (0.18–0.26)

0.12 (0.07–0.17)

0.13 (0.07–0.18)

0.06 (0.01–0.12)

0.20 (0.13–0.27)

0.14 (0.09–0.19)

0.09 (0.02–0.16)

  Daily

0.64 (0.59–0.69)

0.86 (0.81–0.91)

0.87 (0.82–0.93)

0.94 (0.88–0.99)

0.64 (0.56–0.73)

0.82 (0.76–0.87)

0.90 (0.83–0.97)

 Bronchodilator use

  Not at all

0.30 (0.25–0.34)

0.10 (0.05–0.14)

0.10 (0.05–0.14)

0.02 (0.00–0.05)

0.39 (0.30–0.49)

0.17 (0.12–0.23)

0.05 (0.00–0.11)

  Occasionally

0.67 (0.62–0.72)

0.75 (0.69–0.82)

0.59 (0.52–0.67)

0.57 (0.46–0.68)

0.61 (0.51–0.70)

0.54 (0.47–0.62)

0.45 (0.34–0.56)

  Daily

0.04 (0.01–0.06)

0.15 (0.09–0.21)

0.31 (0.23–0.38)

0.49 (0.38–0.60)

0.00 (0.00–0.01)

0.28 (0.21–0.35)

0.50 (0.39–0.61)

 Oral corticosteroid prescriptions

  0 prescriptions

0.97 (0.94–0.99)

0.41 (0.32–0.49)

0.78 (0.71–0.84)

0.11 (0.03–0.18)

1.00 (0.98–1.00)

0.90 (0.86–0.95)

0.28 (0.16–0.40)

  1 to 2 prescriptions

0.03 (0.00–0.05)

0.57 (0.49–0.66)

0.15 (0.09–0.21)

0.53 (0.41–0.65)

0.00 (0.00–0.02)

0.09 (0.04–0.13)

0.51 (0.39–0.63)

  ≥3 prescriptions

0.00 (0.00–0.00)

0.02 (0.00–0.05)

0.02 (0.00–0.03)

0.32 (0.21–0.43)

0.00 (0.00–0.00)

0.01 (0.00–0.02)

0.16 (0.08–0.24)

  Daily oral corticosteroid medication

0.01 (0.00–0.02)

0.00 (0.00–0.00)

0.06 (0.03–0.09)

0.04 (0.00–0.09)

0.00 (0.00–0.00)

0.00 (0.00–0.01)

0.05 (0.00–0.10)

 Antibiotics use

  0 prescription

0.98 (0.95–1.00)

0.42 (0.33–0.52)

0.97 (0.93–1.01)

0.08 (0.00–0.19)

0.99 (0.97–1.01)

0.95 (0.92–0.99)

0.37 (0.23–0.50)

  1 prescription

0.01 (0.00–0.03)

0.32 (0.25–0.40)

0.02 (0.00–0.05)

0.08 (0.00–0.16)

0.01 (0.00–0.03)

0.04 (0.01–0.06)

0.24 (0.14–0.33)

  2 prescriptions

0.01 (0.00–0.02)

0.17 (0.11–0.22)

0.01 (0.00–0.03)

0.20 (0.10–0.29)

0.00 (0.00–0.01)

0.01 (0.00–0.02)

0.19 (0.10–0.27)

  3 or more prescriptions

0.00 (0.00–0.01)

0.09 (0.04–0.14)

0.00 (0.00–0.03)

0.64 (0.49–0.78)

0.00 (0.00–0.00)

0.00 (0.00–0.01)

0.21 (0.12–0.30)

 St. George’s Scoreb

  0–7 points

0.48 (0.41–0.55)

0.15 (0.10–0.21)

0.03 (0.01–0.05)

0.00 (0.00–0.01)

0.59 (0.47–0.72)

0.14 (0.08–0.20)

0.07 (0.01–0.13)

  >7–15 points

0.32 (0.27–0.38)

0.31 (0.24–0.37)

0.15 (0.13–0.18)

0.09 (0.02–0.16)

0.21 (0.12–0.31)

0.26 (0.20–0.33)

0.04 (0.00–0.09)

  >15–27 points

0.15 (0.10–0.21)

0.35 (0.28–0.42)

0.36 (0.28–0.43)

0.17 (0.08–0.27)

0.19 (0.09–0.28)

0.27 (0.20–0.33)

0.28 (0.18–0.38)

  >27 points

0.04 (0.01–0.08)

0.19 (0.11–0.27)

0.49 (0.39–0.58)

0.74 (0.63–0.85)

0.00 (0.00–0.03)

0.33 (0.26–0.41)

0.62 (0.51–0.73)

 Health care facility use score

  0 point

0.97 (0.94–0.99)

0.36 (0.27–0.45)

0.88 (0.82–0.94)

0.13 (0.04–0.22)

0.96 (0.92–1.00)

0.92 (0.87–0.97)

0.37 (0.26–0.49)

  1 point

0.03 (0.01–0.06)

0.21 (0.15–0.27)

0.07 (0.03–0.11)

0.03 (0.00–0.07)

0.04 (0.01–0.08)

0.03 (0.00–0.06)

0.12 (0.05–0.19)

  2 to 3 points

0.00 (0.00–0.00)

0.38 (0.30–0.46)

0.05 (0.01–0.09)

0.48 (0.37–0.59)

0.00 (0.00–0.01)

0.05 (0.01–0.08)

0.34 (0.24–0.44)

  ≥4 points

0.00 (0.00–0.00)

0.05 (0.02–0.08)

0.00 (0.00–0.02)

0.36 (0.25–0.47)

0.00 (0.00–0.00)

0.00 (0.00–0.00)

0.17 (0.09–0.25)

  1. Probabilities over 50% or otherwise important for the characterization of each subtype are marked in bold
  2. aAsthma controller medication use includes both inhaled corticosteroids and combination medication of inhaled corticosteroid and long-acting beta-agonist
  3. bSt. George’s score range: 0-100